79946-50-2Relevant articles and documents
A Convenient Synthesis of Unsaturated 2,4-Disubstituted 2-Imidazolin-5-ones
Devasia, Ganapathiplackal M.,Shafi, P. Mohamed
, p. 657 - 660 (2007/10/02)
Twenty five unsaturated 2,4-disubstituted 2-imidazolin-5-ones (IV) have been prepared in 23-71percent yields by condensing aromatic aldehydes with a mixture of ethyl chloroacetate and an aromatic amidinium chloride in the presence of sodium hydrogencarbonate.Twenty three of them have also been prepared in 62-97percent yields by this method using ethyl bromoacetate instaed of the chloroacetate.Further, two unsaturated 2-imidazolin-5-ones (IV) have been prepared by these two methods using cyclohexanone (yields 33percent each) and cinnamaldehyde (yields 0 and 18percent) instead of the aromatic aldehydes.
