80004-04-2 Usage
Description
(S)-1,4,7,10,13,16-Hexaoxacyclooctadecane-2-methanol, also known as crown-6 ether, is a cyclic polyether chemical compound with the molecular formula C12H24O6. It features a crown-like structure composed of six oxygen atoms, which grants it unique properties and applications in various fields.
Uses
Used in Organic Synthesis:
Crown-6 ether is utilized as a phase transfer catalyst, facilitating reactions between organic compounds and other reagents that may not be soluble in the same phase. This enhances the efficiency and scope of organic synthesis processes.
Used in Coordination Chemistry:
As a complexing agent, crown-6 ether forms stable complexes with metal ions, particularly alkali and alkaline earth metal ions. This property is valuable in coordination chemistry for studying the properties and reactivity of metal ions and their complexes.
Used in Metal Ion Extraction:
Crown-6 ether is employed in the extraction of metal ions from various solutions, capitalizing on its selective cation-binding ability. This application is crucial in the purification and separation of metal ions in industrial processes.
Used in Supramolecular Chemistry:
In the field of supramolecular chemistry, crown-6 ether serves as a host molecule in host-guest chemistry, enabling the study of non-covalent interactions and the design of complex molecular assemblies.
Used in Chemical Separation and Purification:
Crown-6 ether is a component in the separation and purification of chemicals, where its selective cation-binding capability aids in the isolation and concentration of specific ions or molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 80004-04-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,0,0 and 4 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 80004-04:
(7*8)+(6*0)+(5*0)+(4*0)+(3*4)+(2*0)+(1*4)=72
72 % 10 = 2
So 80004-04-2 is a valid CAS Registry Number.
InChI:InChI=1/C13H26O7/c14-11-13-12-19-8-7-17-4-3-15-1-2-16-5-6-18-9-10-20-13/h13-14H,1-12H2/t13-/m0/s1
80004-04-2Relevant articles and documents
Biomimetic Studies Using Artificial Systems. II. Enantioselective Thiolysis of D- or L-α-Amino Acid Ester Salts by Thiol-Bearing Chiral Crown Ethers as an Enzyme Model
Sasaki, Shigeki,Kawasaki, Motoji,Koga, Kenji
, p. 4247 - 4266 (2007/10/02)
The rates of transacylation were studied between thiol-bearing chiral crown ethers (1-10) and α-amino acid p-nitrophenyl ester salts.Enantioselectivities, kD/kL ratios, of 6.5 for valine ester salt, 8.7 for phenylalanine ester salt, and 7.7 for valine ester salt were achieved by 1, 5, and 8, respectively.Saturation phenomena of rate acceleration depending on crown concentration were observed and analysis of these data revealed that the chiral recognition occurs in the step of liberation of p-nitrophenol by intra-complex thiolysis, not in the complex-forming step.A possible mechanism for the anantioselectivity is proposed on the basis of the kinetic data.Keywords - crown ether; transacylation; pseudo-first-order rate constant; enantioselectivity; thiolysis; intra-complex reaction; enzyme model
