80030-92-8

Basic information

• Product Name: 3H-Pyrazol-3-one, 1,2-dihydro-2-methyl-5-phenyl-
• CAS NO: 80030-92-8
• Molecular Formula: C10H10N2O
• Molecular Weight: 174.202
• Mol File: 80030-92-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3H-Pyrazol-3-one, 1,2-dihydro-2-methyl-5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3H-Pyrazol-3-one, 1,2-dihydro-2-methyl-5-phenyl-(80030-92-8)
• EPA Substance Registry System: 3H-Pyrazol-3-one, 1,2-dihydro-2-methyl-5-phenyl-(80030-92-8)

Safety Data

• Hazardous Substances Data: 80030-92-8(Hazardous Substances Data)

Upstream product

• 53256-19-2 ethyl (Z)-3-amino-3-phenylacrylate 
• 60-34-4 methylhydrazine 
• 80030-91-7 (E,Z)-5-Benzylidene-3-benzyl-2,4-dioxo-1,3-thiazolidine 
• 24289-21-2 (E,Z)-5-Benzylidene-3-allyl-2,4-dioxo-1,3-thiazolidine 
• 55547-89-2 (E,Z)-5-Benzylidene-3-ethyl-2,4-dioxo-1,3-thiazolidine 
• 27412-71-1 5-phenyl-1H-pyrazol-3(2H)-one 
• 74-88-4 methyl iodide 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 79994-66-4 3-phenyl-1,2,4-trimethylpyrazolin-3-one 
• 59803-60-0 5-Chloro-1-methyl-3-phenylpyrazole 

Relevant articles and documents

Reactivity of p-Phenyl Substituted β-Enamino Compounds using K-10/ultrasound. I. Synthesis of Pyrazoles and Pyrazolinones

The reactivity of the β-enamino ketones, 3-amino-l-(p-phenyl-substituted)-2-buten-l-ones la-d and β-enamino esters. Ethyl-3-amino-3-(p-phenyl-substituted)-2-propenoates 5a-d were evaluated by systematic studies of the reactions with hydrazine and methylhydrazine by reactions with solid support K-10/ultrasound and homogeneous media (reflux in ethanol or dichloromethane) yielding pyrazole rings 2a-d, Af-methylpyrazoles 3a-d, 4a-d and N-methylpyrazolinones 6a-c and 7a-c. The regiochemistry of the cyclization showed dependence of the reaction conditions employed as well as the substituent in the aromatic ring.

A New Synthetic Route to 3-Oxo-5-phenyl-2,3-dihydropyrazoles

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