80049-46-3

Basic information

• Product Name: 2-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-1,2,4-triazolin-3-one
• CAS NO: 80049-46-3
• Molecular Weight: 529.506
• Mol File: 80049-46-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-1,2,4-triazolin-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-1,2,4-triazolin-3-one(80049-46-3)
• EPA Substance Registry System: 2-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-1,2,4-triazolin-3-one(80049-46-3)

Safety Data

• Hazardous Substances Data: 80049-46-3(Hazardous Substances Data)

Upstream product

• 70832-64-3 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose 
• 80049-41-8 4-trimethylsilanyl-3-trimethylsilanyloxy-4H-[1,2,4]triazole 
• 6974-32-9 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose 
• 930-33-6 2,4-dihydro-1,2,4-triazol-3-one 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 

Relevant articles and documents

Ribofuranosyl triazolone: A natural product herbicide with activity on adenylosuccinate synthetase following phosphorylation

2,4-Dihydro-4-(β-D-ribofuranosyl)-1,2,4(3H)-triazol-3-one (2) was identified as the principal phytotoxic component of a fermentation broth derived from an Actinomadura. The compound is a new natural product, but known by synthesis. Bread-spectrum herbicidal activity was demonstrated in greenhouse tests. Metabolite reversal studies suggested the target site was adenylosuccinate synthetase, which was confirmed by direct measurement of the activity of the 5'-phosphorylated derivative on the isolated enzyme.