80053-63-0Relevant articles and documents
α-Functionalization of Cyclic Secondary Amines: Lewis Acid Promoted Addition of Organometallics to Transient Imines
Paul, Anirudra,Seidel, Daniel
, p. 8778 - 8782 (2019/06/07)
Cyclic imines, generated in situ from their corresponding N-lithiated amines and a ketone hydride acceptor, undergo reactions with a range of organometallic nucleophiles to generate α-functionalized amines in a single operation. Activation of the transient imines by Lewis acids that are compatible with the presence of lithium alkoxides was found to be crucial to accommodate a broad range of nucleophiles including lithium acetylides, Grignard reagents, and aryllithiums with attenuated reactivities.
Successive Beckmann Rearrangement-Alkylation Sequence by Organoaluminium Reagnts. A Simple Route to dl-Pumiliotoxin C
Hattori, Kazunobu,Matsumura, Yasushi,Miyazaki, Tohru,Maruoka, Keiji,Yamamoto, Hisashi
, p. 7368 - 7370 (2007/10/02)
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