80054-94-0

Basic information

• Product Name: 2,2,2-trifluoroethyl naphthalene-1-carboxylate
• CAS NO: 80054-94-0
• Molecular Formula: C₁₃H₉F₃O₂
• Molecular Weight: 254.2046
• Mol File: 80054-94-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 303.2°C at 760 mmHg
• Flash Point: 120.3°C
• Density: 1.308g/cm³
• Vapor Pressure: 0.000944mmHg at 25°C
• Refractive Index: 1.539
• CAS DataBase Reference: 2,2,2-trifluoroethyl naphthalene-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,2-trifluoroethyl naphthalene-1-carboxylate(80054-94-0)
• EPA Substance Registry System: 2,2,2-trifluoroethyl naphthalene-1-carboxylate(80054-94-0)

Safety Data

• Hazardous Substances Data: 80054-94-0(Hazardous Substances Data)

Usage

General Description

2,2,2-trifluoroethyl naphthalene-1-carboxylate is a chemical compound that is derived from naphthalene-1-carboxylic acid and trifluoroethanol. It is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 2,2,2-trifluoroethyl naphthalene-1-carboxylate is a clear and colorless liquid with a high boiling point, making it suitable for use in high-temperature reactions. It is a versatile building block for the production of a wide range of organic compounds and is commonly used in the pharmaceutical and agricultural industries for its unique chemical properties. Its ability to react with a variety of functional groups makes it a valuable compound for chemical synthesis and research applications.

Upstream product

• 371-67-5 2,2,2-trifluorodiazoethane 
• 86-55-5 1-naphthalenecarboxylic acid 
• 75-89-8 2,2,2-trifluoroethanol 
• 879-18-5 naphthalene-1-carbonic acid chloride 
• 4780-79-4 1-naphthalene methanol 

Relevant articles and documents

Trifluoroacetaldehyde N-Tosylhydrazone as a Precursor of Trifluorodiazoethane in Reactions of Insertion into the Heteroatom-Hydrogen Bond

Trifluorodiazoethane is a widely explored trifluoroethylating reagent, which is suitable for the preparation of a large number of fluorine-containing organic molecules. Nevertheless, CF3CHN2 has some disadvantages, such as volatility

Facile oxidative conversion of alcohols to esters using molecular iodine

A simple, efficient, and high-yield procedure for the oxidative conversion of alcohols to various types of esters and ketones, with molecular iodine and potassium carbonate was successfully carried out.

Solvolyses of naphthoyl chlorides. Solvent effect and Grunwald-Winstein correlation analyses with YxBnCl scales

The solvolyses of 1-naphthoyl (2), 2-naphthoyl (3), 4-methyl-1-naphthoyl (4) and 6-methoxy-2-naphthoyl (5) chlorides in a variety of solvents were studied, and correlation analyses by using the single- and dual-parameter Grunwald-Winstein equations were examined. An excellent linear relationship (R = 0.995) for 4, log (k/k0) = 0.733YxBnCl + 0.269NOTs, was observed. An SN1-like mechanism with decreasing extent of nucleophilic solvent participation was found in the solvolysis of 2 and 4.2-Naphthoyl chloride is likely to have a mechanism at the borderline of SN1-like dissociation and an addition-elimination process. 6-Methoxy-2-naphthoyl chloride shows more SN1-like character than 3 and is associated with nucleophilic solvent intervention more pronounced than that for 2 and 4. The applicability and the advantages of using the YxBnCl scale for different types of substrates are discussed. Copyright