801218-74-6

Basic information

• Product Name: 4H-1-Benzopyran-4-one, 7-methoxy-2-[4-methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) phenyl]-
• CAS NO: 801218-74-6
• Molecular Formula: C23H25BO6
• Molecular Weight: 408.259
• Mol File: 801218-74-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4H-1-Benzopyran-4-one, 7-methoxy-2-[4-methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-Benzopyran-4-one, 7-methoxy-2-[4-methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) phenyl]-(801218-74-6)
• EPA Substance Registry System: 4H-1-Benzopyran-4-one, 7-methoxy-2-[4-methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) phenyl]-(801218-74-6)

Safety Data

• Hazardous Substances Data: 801218-74-6(Hazardous Substances Data)

Upstream product

• 801218-77-9 7-hydroxy-2-(3-iodo-4-methoxy-phenyl)-chromen-4-one 
• 123-11-5 4-methoxy-benzaldehyde 
• 2314-37-6 3-iodo-4-methoxybenzaldehyde 
• 25015-92-3 2-chloro-1-(2,4-dihydroxyphenyl)ethanone 
• 15837-61-3 3'-iodo-4',7-dimethoxyflavone 
• 73183-34-3 bis(pinacol)diborane 
• 108-46-3 recorcinol 

Relevant articles and documents

Synthesis of gem-difluoromethylenated biflavonoid via the Suzuki coupling reaction

gem-Difluoromethylenated biflavonoid 1 was synthesized via the Suzuki coupling reaction. The key intermediate 6-iodonated flavone 4 was regioselectively synthesized by the use of AgOAc/I2 under mild conditions without handling of a strongly toxic reagent. The key step was the formation of a flavone 3′-boronate 3 using a palladium-catalyzed exchange of the corresponding 3′-iodonated flavone with a diboron reagent.