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80177-51-1

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  • [(13S,16R,17R)-3,16-dihydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-methyl-azanium; (Z)-4-hydroxy-4-oxo-but-2-enoate

    Cas No: 80177-51-1

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  • [(13S,16R,17R)-3,16-dihydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-methyl-azanium; (Z)-4-hydroxy-4-oxo-but-2-enoate

    Cas No: 80177-51-1

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80177-51-1 Usage

Description

[3,16alpha-dihydroxyestra-1,3,5(10)-trien-17beta-yl](methyl)ammonium hydrogen maleate is a synthetic derivative of the female sex hormone, estrogen, with a methylated ammonium group and a hydrogen maleate moiety. It is a chemical compound that holds potential therapeutic effects on hormone-related conditions.

Uses

Used in Pharmaceutical Applications:
[3,16alpha-dihydroxyestra-1,3,5(10)-trien-17beta-yl](methyl)ammonium hydrogen maleate is used as a therapeutic agent for hormone-related conditions such as menopausal symptoms, osteoporosis, and certain types of cancer. It targets the hormonal imbalances and provides relief from associated symptoms.
Used in Hormone Replacement Therapy:
[3,16alpha-dihydroxyestra-1,3,5(10)-trien-17beta-yl](methyl)ammonium hydrogen maleate is being studied for its potential use in hormone replacement therapy, where it could help in restoring hormonal balance in individuals experiencing menopausal symptoms or other hormone deficiency conditions.
Used in Contraceptive Development:
Additionally, [3,16alpha-dihydroxyestra-1,3,5(10)-trien-17beta-yl](methyl)ammonium hydrogen maleate is being explored for its potential application in the development of contraceptives, leveraging its hormonal properties to prevent pregnancy.

Check Digit Verification of cas no

The CAS Registry Mumber 80177-51-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,1,7 and 7 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 80177-51:
(7*8)+(6*0)+(5*1)+(4*7)+(3*7)+(2*5)+(1*1)=121
121 % 10 = 1
So 80177-51-1 is a valid CAS Registry Number.

80177-51-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 17β-(methylamino)estra-1,3,5(10)-triene-3,16α-diol maleate

1.2 Other means of identification

Product number -
Other names (8R,9S,13S,14S,16R,17R)-13-Methyl-17-methylamino-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,16-diol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:80177-51-1 SDS

80177-51-1Upstream product

80177-51-1Downstream Products

80177-51-1Relevant articles and documents

Novel 17-amino-16-hydroxy steroids of the androstane and oestrane series and derivatives thereof

-

, (2008/06/13)

New and pharmacologically useful 17-amino-16-hydroxy-steroids of the androstane and oestrane series are disclosed having the formula I: STR1 and pharmaceutically acceptable non-toxic acid addition salts thereof, wherein: R1 =H or hydrocarbyl of one to six carbon atoms (preferably lower alkyl, such as methyl); R2 =H or hydrocarbyl of one to six carbon atoms (preferably lower alkyl, such as methyl); R3 =a free, esterified or etherified hydroxyl group; ring A inclusive carbon atoms 6 and 9 has one of the following configurations: STR2 in which R4 =a free, esterified or etherified hydroxyl group; R5 =O or H(R7), wherein R7 is a free, esterified or etherified hydroxyl group; R6 =H or methyl; and the dotted lines represent an optional double bond in 4,5- or 5,6-position; as well as the enantiomers and racemates of these steroids. The novel compounds have antiarrhythmic properties.

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