80243-73-8

Basic information

• Product Name: 5-(3-hydroxypropyl)-2-Pyrrolidinone
• Synonyms: 5-(3-hydroxypropyl)-2-Pyrrolidinone
• CAS NO: 80243-73-8
• Molecular Weight: 143.186
• Mol File: 80243-73-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(3-hydroxypropyl)-2-Pyrrolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3-hydroxypropyl)-2-Pyrrolidinone(80243-73-8)
• EPA Substance Registry System: 5-(3-hydroxypropyl)-2-Pyrrolidinone(80243-73-8)

Safety Data

• Hazardous Substances Data: 80243-73-8(Hazardous Substances Data)

Upstream product

• 18356-28-0 tetrahydro-pyrrolizin-3,5-dione 

Relevant articles and documents

(E)-5-Hydroxypyrrolizidin-3-one: Versatile Synthon for the Synthesis of 5-Substituted 2-Pyrrolidones and (Z)-3-Alkylpyrrolizidines

Carbinol lactam 6 of secured stereochemistry served as a synthon to prepare 5-substituted 2-pyrrolidones and pyrrolizidin-3-ones.The relative stereochemistry of 6 and the dithioketal 13, prepared from the keto lactam 11, was established by single-crystal X-ray analysis.Desulfurization of the dithioketals 13 and 14 afforded the 5-n-propylpyrrolizidin-3-ones 15 and 16.Reduction of lactam 15 with LiAlH4 gave the racemic (Z)-3-n-propylpyrrolizidine (17), an analogue of a substance recently detected in ant species.