80254-31-5

Basic information

• Product Name: 4H-1,3-Oxazine, 2-(4-chlorophenyl)-5,6-dihydro-
• CAS NO: 80254-31-5
• Molecular Formula: C10H10ClNO
• Molecular Weight: 195.648
• Mol File: 80254-31-5.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 4H-1,3-Oxazine, 2-(4-chlorophenyl)-5,6-dihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1,3-Oxazine, 2-(4-chlorophenyl)-5,6-dihydro-(80254-31-5)
• EPA Substance Registry System: 4H-1,3-Oxazine, 2-(4-chlorophenyl)-5,6-dihydro-(80254-31-5)

Safety Data

• Hazardous Substances Data: 80254-31-5(Hazardous Substances Data)

Upstream product

• 125775-23-7 N-(3-bromopropyl)-p-chlorobenzamide 
• 39887-52-0 4-chloro-N-(3-hydroxypropyl)benzamide 
• 623-03-0 4-Cyanochlorobenzene 
• 156-87-6 propan-1-ol-3-amine 
• 122-01-0 4-chloro-benzoyl chloride 
• 74-11-3 para-chlorobenzoic acid 
• 4231-70-3 p-chlorobenzoyl-1H-1,2,3-benzotriazole 
• 80265-27-6 Trifluoro-methanesulfonate14-[3-(4-chloro-benzoylamino)-propyl]-7-phenyl-5,6,8,9-tetrahydro-dibenzo[c,h]acridinium; 

Relevant articles and documents

A 2 - substituted oxazoline or 2 - substituted piperazine synthetic method (by machine translation)

The invention discloses a method for synthesizing 2 - substituted oxazoline or 2 - substituted oxazine new method, by nitrile and amino ethanol or 3 - amino - 1 - propanol as raw material, in the absence of solvent, can be used for the recycling of the sulfur to induce synthesis of 2 - substituted oxazoline and 2 - substituted piperazine. The method of the invention has low cost, simple reaction process, mild reaction conditions, the reaction time is short, the yield and the like, is suitable for the industrial generation. (by machine translation)

Microwave-Assisted Synthesis of 2-Aryl-2-oxazolines, 5,6-Dihydro-4H-1,3-oxazines, and 4,5,6,7-Tetrahydro-1,3-oxazepines

The first general procedure for the synthesis of 5- to 7-membered cyclic iminoethers by microwave-assisted cyclization of ω-amido alcohols promoted by polyphosphoric acid (PPA) esters is presented. 2-Aryl-2-oxazolines and 5,6-dihydro-4H-1,3-oxazines were efficiently prepared using ethyl polyphosphate/CHCl3. Trimethylsilyl polyphosphate in solvent-free conditions allowed for the synthesis of hitherto-unreported 4,5,6,7-tetrahydro-1,3-oxazepines. The method involves good to excellent yields and short reaction times.The reaction mechanism and the role of PPA esters were investigated in a chiral substrate.

A green and selective synthesis of 2-aryloxazines and 2- aryltetrahydropyrimidines

An efficient method for the selective synthesis of 2-substituted oxazines and tetrahydropyrimidines by the reaction of arylnitriles with 3-amino-1-propanol and 1,3-diaminopropane in the presence of montmorillonite K-10 and KSF as inexpensive, environmenta