80355-74-4 Usage
Description
(1E)-bis(2-methylbenzylidene)hydrazine, a hydrazine derivative with the molecular formula C15H16N2, is a yellow crystalline compound that is sparingly soluble in water. It can exist in both the E and Z isomeric forms and is known for its potential applications in coordination chemistry, organic synthesis, and metal-organic frameworks.
Uses
Used in Coordination Chemistry:
(1E)-bis(2-methylbenzylidene)hydrazine is used as a ligand for the formation of coordination compounds. Its ability to chelate with metal ions allows for the creation of stable complexes with potential applications in various fields.
Used in Organic Synthesis:
(1E)-bis(2-methylbenzylidene)hydrazine is employed as a synthetic building block in organic chemistry. Its reactivity and structural features make it a valuable component in the synthesis of various organic compounds.
Used in Metal-Organic Frameworks (MOFs):
(1E)-bis(2-methylbenzylidene)hydrazine is utilized as a component in the construction of metal-organic frameworks. These porous materials have potential applications in gas storage, catalysis, and drug delivery due to their high surface area and tunable properties.
Used in Pharmaceutical Research:
(1E)-bis(2-methylbenzylidene)hydrazine is studied for its biological activity, particularly as an anti-cancer agent. Its potential to target and inhibit the growth of cancer cells is under investigation, although further research is needed to fully understand its therapeutic potential and associated risks.
Check Digit Verification of cas no
The CAS Registry Mumber 80355-74-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,3,5 and 5 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 80355-74:
(7*8)+(6*0)+(5*3)+(4*5)+(3*5)+(2*7)+(1*4)=124
124 % 10 = 4
So 80355-74-4 is a valid CAS Registry Number.
80355-74-4Relevant articles and documents
Ruthenium(ii)-catalysed 1,2-selective hydroboration of aldazines
Gunanathan, Chidambaram,Pradhan, Subham,Thiyagarajan, Subramanian
supporting information, p. 7147 - 7151 (2021/08/30)
Herein, an efficient and simple catalytic method for the selective and partial reduction of aldazines using ruthenium catalyst [Ru(p-cymene)Cl2]2 (1) has been accomplished. Under mild conditions, aldazines undergo the addition of pinacolborane in the presence of a ruthenium catalyst, which delivered N-boryl-N-benzyl hydrazone products. Notably, the reaction is highly selective, and results in exclusive mono-hydroboration and desymmetrization of symmetrical aldazines. Mechanistic studies indicate the involvement of in situ formed intermediate [{(η6-p-cymene)RuCl}2(μ-H-μ-Cl)] (1a) in this selective hydroboration.
Monohydrocyanation of symmetrical azines using potassium hexacyanoferrate(II) as an environmentally friendly cyanide source
Hu, Xiaochun,Li, Hongbo,Yang, Jingya,Li, Zheng
supporting information, p. 1786 - 1790 (2014/08/05)
The monohydrocyanation of symmetrical azines to synthesize α-hydrazinonitriles using potassium hexacyanoferrate(II) as cyanide source and benzoyl chloride as a promoter under catalyst-free conditions is described. The advantages of this protocol are the environmentally friendly cyanide source, high yield, and simple work-up procedure. Georg Thieme Verlag Stuttgart New York.
Synthesis of N-imino-β-lactams from 2,3-diaza-1,3-dienes (azines) mediated by POCl3
Sharma,Anand,Kaur, Gurpreet
, p. 1273 - 1275 (2008/09/21)
Symmetrically substituted azines derived from aromatic aldehydes have been found compatible with the reaction of phenoxyacetic acid activated by POCl 3. N-Imino-β-lactams are efficiently obtained by this method in good to excellent yields with varying levels of cis, trans-selectivity.
