80357-26-2

Basic information

• Product Name: 3-Pyridinecarboxamide, N,1-dicyclohexyl-1,6-dihydro-2,4-dimethyl-6-oxo-
• CAS NO: 80357-26-2
• Molecular Formula: C20H30N2O2
• Molecular Weight: 330.47
• Mol File: 80357-26-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Pyridinecarboxamide, N,1-dicyclohexyl-1,6-dihydro-2,4-dimethyl-6-oxo-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarboxamide, N,1-dicyclohexyl-1,6-dihydro-2,4-dimethyl-6-oxo-(80357-26-2)
• EPA Substance Registry System: 3-Pyridinecarboxamide, N,1-dicyclohexyl-1,6-dihydro-2,4-dimethyl-6-oxo-(80357-26-2)

Safety Data

• Hazardous Substances Data: 80357-26-2(Hazardous Substances Data)

Upstream product

• 1132-42-9 N-cyclohexylacetoacetamide 

Relevant articles and documents

Preparation and Antiinflammatory Activity of 2- and 4-Pyridones

Several N-alkyl- and N-arylacetoamides have been self-condensed to form pyridones.N-Alkylacetoacetamides give 2-pyridones, while N-arylacetoamides give 4-pyridones.In an attempt to develop nonacidic, nonsteroidal antiinflammatory agents, the pyridones were tested in a carrageenan-induced pedal edema assay in rats.While the 2-pyridones were not active, 9 of 17 4-pyridones tested were active, and one compound (4g) had antiinflammatory efficacy in a dose-response assay (ED50 values).Most compounds were considered nontoxic by determination of approximate LD50 values in mice by a standard multidimensional observational assay.