80392-33-2

Basic information

• Product Name: 1-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzene
• Synonyms: 1-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzene
• CAS NO: 80392-33-2
• Molecular Weight: 240.299
• Mol File: 80392-33-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzene(80392-33-2)
• EPA Substance Registry System: 1-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzene(80392-33-2)

Safety Data

• Hazardous Substances Data: 80392-33-2(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 123824-57-7 1-bromo-9-phenyl-3,6,9-trioxanonane 
• 62921-76-0 2,5,8,11-tetraoxatridecan-13-ol tosylate 
• 108-95-2 phenol 
• 2243-44-9 2-(2-phenoxyethoxy)ethyl chloride 
• 139-02-6 sodium phenoxide 
• 104-68-7 2-(2-phenoxyethoxy)ethanol 
• 7204-16-2 2-(2-(2-phenoxyethoxy)ethoxy)ethan-1-ol 
• 72593-77-2 3,6,9-trioxadecyl bromide 
• 112-35-6 triethylene glucol monomethyl ether 
• 71-43-2 benzene 
• 123824-56-6 1-bromo-6-phenyl-3,6-dioxahexane 

Downstream Products

• 128134-65-6 p-nitrophenyl {2-[2-(2-methoxyethoxy)ethoxy]ethyl}ether 
• 128134-64-5 1-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)-2-nitrobenzene 
• 125808-05-1 1-bromo-4-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzene 

Relevant articles and documents

TRPML MODULATORS

The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.

The Development of a New Nitrating Agent: The Unusual Regioselective Nitration of Diphenylpolyethylene Glycols and Phenylpolyethylene Glycols with Trimethylsilyl Nitrate - BF3OEt2

We have investigated the nitration of the following podands, 1-phenoxy-8-(2'-nitrophenoxy)-, 1-phenoxy-8-(4'-nitrophenoxy)-, and 1-(2',4'-dinitrophenoxy)-8-phenoxy-3,6-dioxaoctane (2, 3, and 4), and 1-(2',4'-dinitrophenoxy)-11-phenoxy-3,6,9-trioxaundecane (5), 1-phenoxy-3,6,9-trioxadecane (6), and 1-phenoxy-3,6,9,12-tetraoxatridecane (7), with trimethylsilyl nitrate catalyzed by BF3OEt2, which is soluble in nonpolar solvents.The reaction selectivity was measured by the ortho:para ratio of the nitrated products and was unusually large in CCl4.The structures of all isolated products, 1,8-bis(2'-nitrophenoxy)-, 1-(2'-nitrophenoxy)-8-(4'-nitrophenoxy)-, 1,8-bis(4'-nitrophenoxy)-, 1-(2',4'-dinitrophenoxy)-8-(2'-nitrophenoxy)-, and 1-(2',4'-dinitrophenoxy)-8-(4'-nitrophenoxy)-3,6-dioxaoctane (8, 9, 10, 11, and 12), 1-(2',4'-dinitrophenoxy)-11-(2'-nitrophenoxy)- and 1-(2',4'-dinitrophenoxy)-11-(4'-nitrophenoxy)-3,6,9-trioxaundecane (13 and 14), 1-(2'-nitrophenoxy)- and 1-(4'-nitrophenoxy)-3,6,9-trioxadecane (15 and 16), and 1-(2'-nitrophenoxy)- and 1-(4'-nitrophenoxy)-3,6,9,12-tetraoxatridecane (17 and 18), were confirmed by the independent preparation of these compounds using a modification of Joeger's method.We have invented a new nitrating system (trimethylsilyl nitrate and BF3OEt2) and have shown that the selectivity (o/p ratio of nitrated products) is unusually high in CCl4.

1H NMR Studies on the Interactions of Acyclic Polyethers with Dimethyltin Dichloride in Aromatic Solvents

The interactions between various acyclic polyethers, RO(CH2CH2O)nR'(R, R'=CH3, Ph), and dimethyltin dichloride (DMTC) in aromatic solvents have been studied by means of 1H NMR spectroscopy.On the basis of a continuous variation method, the formation of the 1:1 complexes between glymes, CH3O(CH2CH2O)nCH3 (n=2, 3, 4), and DMTC was revealed in benzene.The 2J(119Sn-CH3) values suggested distorted trans-octahedral configurations for these complexes.From the statistical consideration of stability constants, it was found that the coordination occurred virtually through neighboring two oxygen atoms in these complexes.DMTC gave the complexes of both 1:1 and 1:2 glyme/DMTC stoichiometry with glymes (n=5, 6) in benzene and with all glymes employed here in toluene and 1-chloronaphthalene.Coexistence of 1:1 and 1:2 species was also encountered for PhO(CH2CH2O)nCH3 (n=3, 4, 5), whereas no appreciable interaction was observed between PhO(CH2CH2O)nPh (n=2, 3, 4) and DMTC.On the basis of these observations, the additional formation of the 1:2 complexes was assumed to be caused by the bulkiness of polyethers.