80416-46-2

Basic information

• Product Name: 1-[2-(6-Bromo-4-oxo-3-phenyl-3,4-dihydro-quinazolin-2-ylsulfanyl)-acetyl]-3-m-tolyl-urea
• CAS NO: 80416-46-2
• Molecular Weight: 523.41
• Mol File: 80416-46-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[2-(6-Bromo-4-oxo-3-phenyl-3,4-dihydro-quinazolin-2-ylsulfanyl)-acetyl]-3-m-tolyl-urea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2-(6-Bromo-4-oxo-3-phenyl-3,4-dihydro-quinazolin-2-ylsulfanyl)-acetyl]-3-m-tolyl-urea(80416-46-2)
• EPA Substance Registry System: 1-[2-(6-Bromo-4-oxo-3-phenyl-3,4-dihydro-quinazolin-2-ylsulfanyl)-acetyl]-3-m-tolyl-urea(80416-46-2)

Safety Data

• Hazardous Substances Data: 80416-46-2(Hazardous Substances Data)

Upstream product

• 5794-88-7 5-Bromo-2-aminobenzoic acid 
• 103-72-0 phenyl isothiocyanate 
• 18009-07-9 6-bromo-2-mercapto-3-phenylquinazolin-4(3H)-one 
• 5544-33-2 1-chloroacetyl-3-m-tolyl-urea 

Relevant articles and documents

Monoamine Oxidase and Succinate Dehydrogenase Inhibitory Properties of Substituted Mercaptoquinazolones

Twelve 6-substituted-2-(1'-mercaptoacetyl-3'-arylurea)-3-phenyl-4-quinazolones were synthesized by condensation of 6-substituted anthranilic acids and aryl isothiocyanates followed by reaction with chloroacetyl arylurea.These compounds were characterized by their sharp melting points and elemental analyses.All compounds were evaluated for their enzyme inhibitory activity.It was found that all substituted quinazolones at a final concentration of 2 x 10-4 M inhibited in vitro monoamine oxidase and succinate dehydrogenase activity of rat brain homogenates and the degree of inhibition ranged from 11-77percent and 25-53percent, respectively.