80476-91-1

Basic information

• Product Name: 1-benzyl-4-(4-chloro-benzhydryl)-piperazine
• Synonyms: 1-benzyl-4-(4-chloro-benzhydryl)-piperazine
• CAS NO: 80476-91-1
• Molecular Weight: 376.929
• Mol File: 80476-91-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-benzyl-4-(4-chloro-benzhydryl)-piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-4-(4-chloro-benzhydryl)-piperazine(80476-91-1)
• EPA Substance Registry System: 1-benzyl-4-(4-chloro-benzhydryl)-piperazine(80476-91-1)

Safety Data

• Hazardous Substances Data: 80476-91-1(Hazardous Substances Data)

Upstream product

• 303-26-4 N-(4-chlorobenzhydryl)piperazine 
• 10429-82-0 N-benzyl-2-chloro-N-(2-chloroethyl)ethanamine hydrochloride 
• 163837-57-8 (R)-(4-chlorophenyl)(phenyl)methylamine 
• 2759-28-6 1-phenylmethylpiperazine 

Downstream Products

• 941577-03-3 (1-benzyl-piperazine)-4-(2,2,2-trichloroethyl)-carbamate 
• 941577-01-1 C₂₀H₂₀Cl₄N₂O₂ 

Relevant articles and documents

Discriminating non-ylidic carbon-sulfur bond cleavages of sulfonium ylides for alkylation and arylation reactions

A sulfonium ylide participated alkylation and arylation under transition-metal free conditions is described. The disparate reaction pattern allowed the separate activation of non-ylidic S-alkyl and S-aryl bond. Under acidic conditions, sulfonium ylides serve as alkyl cation precursors which facilitate the alkylations. While under alkaline conditions, cleavage of non-ylidic S-aryl bond produces O-arylated compounds efficiently. The robustness of the protocols were established by the excellent compatibility of wide variety of substrates including carbohydrates.