80500-10-3

Basic information

• Product Name: 2-[4-(6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-yI)piperazin-1-yl]-N-(diphenylmethylene)ethanamine
• Synonyms: 2-[4-(6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-yI)piperazin-1-yl]-N-(diphenylmethylene)ethanamine
• CAS NO: 80500-10-3
• Molecular Weight: 293.412
• Mol File: 80500-10-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[4-(6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-yI)piperazin-1-yl]-N-(diphenylmethylene)ethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-(6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-yI)piperazin-1-yl]-N-(diphenylmethylene)ethanamine(80500-10-3)
• EPA Substance Registry System: 2-[4-(6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-yI)piperazin-1-yl]-N-(diphenylmethylene)ethanamine(80500-10-3)

Safety Data

• Hazardous Substances Data: 80500-10-3(Hazardous Substances Data)

Upstream product

• 140-31-8 aminoethylpiperazine 
• 119-61-9 benzophenone 

Downstream Products

• 1388893-02-4 2-[4-(6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-yI)piperazin-1-yl]-N-(diphenylmethylene)ethanamine 

Relevant articles and documents

INTRAMOLECULAR GENERAL-BASE CATALYSIS OF SCHIFF-BASED HYDROLYSIS BY TERTIARY AMINO GROUPS.

Hydrolysis of a series of Schiff bases derived from benzophenone and various amines has been studied kineticlly in aqueous solution. A linear correlation of the log of the rate constants for the water reaction with the Schiff base pK//a (slope minus 0. 70) shows large positive deviations for Schiff bases derived from (2-aminoethyl)diethylamine, N-(2-aminoethyl)morpholine, N-(2-aminoethyl)piperazine and 2-(aminomethyl)pyridine (1i) but small deviations for Schiff bases from N-(3-aminopropyl)morpholine and 2-(2-aminoethyl)pyridine. The deviations found are attributed to intramolecular general-base catalysis of the water reaction by the internal tertiary amino groups. Magnitudes of the rate enhancement are correlated well with pK//a//l of the internal catalyst ( beta equals 0. 49). Effective concentrations of the internal bases are estimated to range from 340 (1e) to 40 M.