80537-08-2Relevant articles and documents
ANTIBACTERIAL COMPOUNDS
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Page/Page column 135, (2017/01/23)
The present invention relates to the following compounds, wherein the integers are as defined in the description, and where the compounds may be useful as medicaments, for instance for use in the treatment of tuberculosis.
Design, Synthesis, and Biological Evaluation of Pyrazolo[1,5-a]pyridine-3-carboxamides as Novel Antitubercular Agents
Tang, Jian,Wang, Bangxing,Wu, Tian,Wan, Junting,Tu, Zhengchao,Njire, Moses,Wan, Baojie,Franzblauc, Scott G.,Zhang, Tianyu,Lu, Xiaoyun,Ding, Ke
supporting information, p. 814 - 818 (2015/07/15)
A series of pyrazolo[1,5-a]pyridine-3-carboxamide derivatives were designed and synthesized as new anti-Mycobacterium tuberculosis (Mtb) agents. The compounds exhibit promising in vitro potency with nanomolar MIC values against the drug susceptive H37Rv s
SUBSTITUTED PYRIMIDINE BMI-1 INHIBITORS
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Page/Page column 124, (2015/03/16)
Amine substituted pyrimidine compounds and forms thereof that inhibit the function and reduce the level of B -cell specific Moloney murine leukemia virus integration site 1 (Bmi-1) protein and methods for their use to inhibit Bmi-1 function and reduce the