80714-55-2 Usage
Description
(S)-1-chloro-3-(1H-imidazol-4-yl)propan-2-amine, also known as R-CHIM, is a chemical compound with the molecular formula C6H10ClN3. It is an amine derivative of imidazole and is commonly used in pharmaceutical research and drug development. R-CHIM is known to have an affinity for the GABA-A receptor, which is a key component in the regulation of neuronal excitability in the central nervous system.
Uses
Used in Pharmaceutical Research:
R-CHIM is used as a research compound for its potential therapeutic applications in the treatment of anxiety and stress-related disorders. Its interaction with the GABA-A receptor suggests that it may help modulate neuronal activity and provide relief from these conditions.
Used in Treatment of Withdrawal Symptoms:
R-CHIM is also being studied for its potential role in reducing symptoms of withdrawal from alcohol and other substances. Its activity on the central nervous system makes it a promising candidate for further investigation into its potential therapeutic uses in this area.
Used in Drug Development:
As a compound with known affinity for the GABA-A receptor, R-CHIM is used in drug development to explore new treatment options for various neurological and psychiatric disorders. Its potential applications in this field are still under investigation, but its unique properties make it a valuable tool in the development of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 80714-55-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,7,1 and 4 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 80714-55:
(7*8)+(6*0)+(5*7)+(4*1)+(3*4)+(2*5)+(1*5)=122
122 % 10 = 2
So 80714-55-2 is a valid CAS Registry Number.
80714-55-2Relevant articles and documents
Histamine analogues. 32nd communication: synthesis and pharmacology of sopromidine, a potent and stereoselective isomer of the achiral H2-agonist impromidine
Elz, Sigurd,Gerhard, Guenter,Schunack, Walter
, p. 259 - 262 (2007/10/02)
Synthesis and pharmacology of sopromidine ((R)-7) and (S)-7, 2 position isomers of impromidine derived from the enantiomeric α-methylhistamines, are reported.The enantiomers of 7 show high stereoselectivity at the atrial H2-receptor of the guinea-pig. (R)-7 is revealed to be a full H2-agonist with 7.4-fold potency relative to histamine, while (S)-7 is a competitive H2-antagonist. chiral H2-agonists / histamine H2-receptor / impromidine analogues / α-methylhistamine
