807283-65-4

Basic information

• Product Name: 1-[2-(3-methoxy-phenyl)-2-oxo-ethyl]-4-phenyl-piperidine-4-carboxylic acid ethyl ester
• CAS NO: 807283-65-4
• Molecular Weight: 381.472
• Mol File: 807283-65-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[2-(3-methoxy-phenyl)-2-oxo-ethyl]-4-phenyl-piperidine-4-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2-(3-methoxy-phenyl)-2-oxo-ethyl]-4-phenyl-piperidine-4-carboxylic acid ethyl ester(807283-65-4)
• EPA Substance Registry System: 1-[2-(3-methoxy-phenyl)-2-oxo-ethyl]-4-phenyl-piperidine-4-carboxylic acid ethyl ester(807283-65-4)

Safety Data

• Hazardous Substances Data: 807283-65-4(Hazardous Substances Data)

Upstream product

• 140-29-4 phenylacetonitrile 
• 77-17-8 Normeperidine 
• 5000-65-7 2-bromo-3'-methoxyacetophenone 
• 24476-55-9 N-(p-tosyl)-4-phenyl-4-cyano-piperidine 
• 84255-02-7 N-tosyl-4-phenylpiperidine-4-carboxylic acid 

Downstream Products

• 132171-52-9 N-<(2-m-Methoxyphenyl-2-hydroxy)ethyl>-4-phenyl-4-carboethoxypiperidine 

Relevant articles and documents

Synthesis and antinociceptive activity of ring substituted N-[(2-phenyl-2-hydroxy)ethyl]-4-phenyl-4-carboethoxypiperidines

A series of phenyl substituted N-[(2-phenyl-2-hydroxy)ethyl]-4-phenyl-4-carboethoxylpiperidine were synthesized and their antinociceptive activity tested in mice and compared with morphine sulphate. All compounds demonstrated antinociceptive activity in both the hot plate and the writhing tests. The studies showed that the antinociceptive activity is dependable on both the nature and the position of the substituent on the phenyl ring. Antagonism study with naloxone, suggests possible interaction of the new compounds with the opioid receptors.