807373-66-6

Basic information

• Product Name: Piperidine, 2-[(2S)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-phenylethyl]-1-methyl-, (2S)-
• CAS NO: 807373-66-6
• Molecular Formula: C20H35NOSi
• Molecular Weight: 333.589
• Mol File: 807373-66-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Piperidine, 2-[(2S)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-phenylethyl]-1-methyl-, (2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperidine, 2-[(2S)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-phenylethyl]-1-methyl-, (2S)-(807373-66-6)
• EPA Substance Registry System: Piperidine, 2-[(2S)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-phenylethyl]-1-methyl-, (2S)-(807373-66-6)

Safety Data

• Hazardous Substances Data: 807373-66-6(Hazardous Substances Data)

Upstream product

• 807373-27-9 2,2,2-trichloroethyl {(1S)-1-[(2S)-2-(tert-butyldimethylsilanoxy)-2-phenylethyl]-7-oxo-7-phenylhept-5(Z)-enyl}(methyl)carbamate 
• 807373-38-2 2,2,2-trichloroethyl {(1S)-1-[(2S)-2-(tert-butyldimethylsilanoxy)-2-phenylethyl]-5-hydroxypentyl}(methyl)carbamate 
• 1026517-23-6 {(S)-1-[(S)-2-(tert-Butyl-dimethyl-silanyloxy)-2-phenyl-ethyl]-5-oxo-pentyl}-methyl-carbamic acid 2,2,2-trichloro-ethyl ester 
• 807373-52-0 2,2,2-trichloroethyl {(1S)-1-[(2S)-2-(tert-butyldimethylsilanoxy)-2-phenylethyl]-5-bromopentyl}(methyl)carbamate 

Downstream Products

• 497-88-1 (-)-sedamine 

Relevant articles and documents

Indirect trapping of the retroconjugate addition reaction intermediate involved in the epimerization of lobeline: Application to the synthesis of (-)-sedamine

Alkyl chloroformates induced indirect trapping of the retroconjugate addition reaction intermediate involved in the epimerization of lobeline is described. This strategy was applied to the conversion of (-)-lobeline to (-)-sedamine in high overall yield.