807640-87-5

Basic information

• Product Name: JNJ 26483327
• Synonyms: BGB 102;BGB102;BGB-102;JNJ 26483327;JNJ26483327;JNJ-26483327;17-Bromo-1,8,9,10,11,12,13,14-octahydro-20-methoxy-13-methyl-4,6-ethenopyrimido[4,5-b][6,1,12]benzoxadiazacyclopentadecine;EOS-60486
• CAS NO: 807640-87-5
• Molecular Formula: C22H25BrN4O2
• Molecular Weight: 457.3635
• Mol File: 807640-87-5.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 582.4±50.0 °C(Predicted)
• Appearance: /
• Density: 1.310±0.06 g/cm3(Predicted)
• PKA: 8.26±0.20(Predicted)
• CAS DataBase Reference: JNJ 26483327(CAS DataBase Reference)
• NIST Chemistry Reference: JNJ 26483327(807640-87-5)
• EPA Substance Registry System: JNJ 26483327(807640-87-5)

Safety Data

• Hazardous Substances Data: 807640-87-5(Hazardous Substances Data)

Usage

General Description

JNJ 26483327 is a potent and selective inhibitor of fatty acid amide hydrolase (FAAH), which is an enzyme involved in the breakdown of endocannabinoids in the body. By inhibiting FAAH, JNJ 26483327 increases the levels of endocannabinoids, which are molecules that play a role in regulating various physiological processes, including pain perception, inflammation, and stress. This chemical has shown promise as a potential treatment for chronic pain, inflammatory conditions, anxiety, and other related disorders in preclinical studies. It is being investigated for its therapeutic potential in a range of conditions related to the endocannabinoid system.