808196-27-2

Basic information

• Product Name: isoquinoline-5-sulfonic acid 2,6-dibromo-4-[2-[(isoquinoline-5-sulfonyl)-methyl-amino]-3-oxo-3-(4-o-tolyl-piperazin-1-yl)-propyl]-phenyl ester
• Synonyms: isoquinoline-5-sulfonic acid 2,6-dibromo-4-[2-[(isoquinoline-5-sulfonyl)-methyl-amino]-3-oxo-3-(4-o-tolyl-piperazin-1-yl)-propyl]-phenyl ester
• CAS NO: 808196-27-2
• Molecular Weight: 893.677
• Mol File: 808196-27-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: isoquinoline-5-sulfonic acid 2,6-dibromo-4-[2-[(isoquinoline-5-sulfonyl)-methyl-amino]-3-oxo-3-(4-o-tolyl-piperazin-1-yl)-propyl]-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: isoquinoline-5-sulfonic acid 2,6-dibromo-4-[2-[(isoquinoline-5-sulfonyl)-methyl-amino]-3-oxo-3-(4-o-tolyl-piperazin-1-yl)-propyl]-phenyl ester(808196-27-2)
• EPA Substance Registry System: isoquinoline-5-sulfonic acid 2,6-dibromo-4-[2-[(isoquinoline-5-sulfonyl)-methyl-amino]-3-oxo-3-(4-o-tolyl-piperazin-1-yl)-propyl]-phenyl ester(808196-27-2)

Safety Data

• Hazardous Substances Data: 808196-27-2(Hazardous Substances Data)

Upstream product

• 808196-26-1 [1-(3,5-dibromo-4-hydroxy-benzyl)-2-oxo-2-(4-o-tolyl-piperazin-1-yl)-ethyl]-methyl-carbamic acid tert-butyl ester 
• 808196-25-0 2-(tert-butoxycarbonyl-methyl-amino)-3-(3,5-dibromo-4-hydroxy-phenyl)-propionic acid methyl ester 
• 123443-09-4 2-(tert-butoxycarbonyl-methyl-amino)-3-(3,5-dibromo-4-hydroxy-phenyl)-propionic acid 
• 112196-59-5 methyl N-(tert-butoxycarbonyl)-N-methyl-L-tyrosinate 
• 39512-51-1 1-(o-toluyl)piperazine 
• 84468-15-5 5-isoquinolinesulfonyl chloride 

Downstream Products

• 808196-28-3 tert-butyl 4-(4-iodo-2-methylphenyl)piperazine-1-carboxylate 
• 808196-30-7 {1-(4-hydroxy-benzyl)-2-[4-(4-iodo-2-methyl-phenyl)-piperazin-1-yl]-2-oxo-ethyl}-methyl-carbamic acid tert-butyl ester 
• 808196-31-8 Isoquinoline-5-sulfonic acid 4-{(S)-3-[4-(4-iodo-2-methyl-phenyl)-piperazin-1-yl]-2-[(isoquinoline-5-sulfonyl)-methyl-amino]-3-oxo-propyl}-phenyl ester 

Relevant articles and documents

Synthesis, radiolabeling, and preliminary biological evaluation of [ 3H]-1-[(S)-N,O-bis-(isoquinolinesulfonyl)-N-methyl-tyrosyl] -4-(o-tolyl)-piperazine, a potent antagonist radioligand for the P2X7 receptor

The design, synthesis, and preliminary biological evaluation of the first potent radioligand antagonist for the P2X7 receptor, named [ 3H]-1-[(S)-N,O-bis-(isoquinolinesulfonyl)-N-methyl-tyrosyl] -4-(o-tolyl)-piperazine (compound 13),