80836-96-0

Basic information

• Product Name: 1-(2,3-Xylyl)piperazine monohydrochloride
• Synonyms: N-(2,3-Dimethylphenyl)-piperazine monohydrochloride;1-(2,3-dimethylphenyl)piperazine dihydrochloride;1-(2,3-xylyl)piperazine hydrochloride;3-DiMethylphenyl)-piperazine Monohydrochloride;1-(2,3-Methylphenyl)piperazine HCl;TIMTEC-BB SBB000676;1-(2,3-XYLYL)PIPERAZINE MONOHYDROCHLORIDE;1-(2,3-DIMETHYLPHENYL)PIPERAZINE HYDROCHLORIDE
• CAS NO: 80836-96-0
• Molecular Formula: C12H19ClN2
• Molecular Weight: 226.75
• Product Categories: PiperazineDerivative;Piperaizine;Piperazine derivates;Building Blocks;Heterocyclic Building Blocks;Piperazines
• Mol File: 80836-96-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: >300 °C(lit.)
• Boiling Point: 95-97°C 0,2mm
• Flash Point: 156.1oC
• Appearance: /
• Density: 0.9306 (rough estimate)
• Vapor Pressure: 8.43E-06mmHg at 25°C
• Refractive Index: 1.5600 (estimate)
• CAS DataBase Reference: 1-(2,3-Xylyl)piperazine monohydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,3-Xylyl)piperazine monohydrochloride(80836-96-0)
• EPA Substance Registry System: 1-(2,3-Xylyl)piperazine monohydrochloride(80836-96-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 80836-96-0(Hazardous Substances Data)

Usage

Uses

1-(2,3-Xylyl)piperazine monohydrochloride may be used in chemical synthesis studies.

InChI:InChI=1/C12H18N2.ClH/c1-10-4-3-5-12(11(10)2)14-8-6-13-7-9-14;/h3-5,13H,6-9H2,1-2H3;1H

Upstream product

• 821-48-7 bis-(2-chloroethyl)amine hydrochloride 
• 87-59-2 2,3-Dimethylaniline 

Downstream Products

• 1352122-44-1 7-{3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propoxy}-2,3-dihydro-1H-cyclopentene[c]benzopyran-4-one 

Relevant articles and documents

Design, synthesis, and biological evaluation of structurally constrained hybrid analogues containing ropinirole moiety as a novel class of potent and selective dopamine D3 receptor ligands

Two series of hybrid analogues were designed, synthesized, and evaluated as a novel class of selective ligands for the dopamine D3 receptor. Binding affinities of target compounds were determined (using the method of radioligand binding assay). Compared to comparator agent BP897, compounds 2a and 2c were found to demonstrate a considerable binding affinity and selectivity for D3 receptor, and especially compound 2h was similarly potent and more selective D3R ligand than BP897, a positive reference. Thus, they may provide valuable information for the discovery and development of highly potent dopamine D3 receptor ligands with outstanding selectivity.