80883-92-7

Basic information

• Product Name: 4-(3-(4-methoxyphenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide
• Synonyms: 4-(3-(4-methoxyphenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide
• CAS NO: 80883-92-7
• Molecular Weight: 407.493
• Mol File: 80883-92-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4-(3-(4-methoxyphenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-(4-methoxyphenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide(80883-92-7)
• EPA Substance Registry System: 4-(3-(4-methoxyphenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide(80883-92-7)

Safety Data

• Hazardous Substances Data: 80883-92-7(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 959-23-9 4'-methoxychalcone 
• 17852-52-7 4-hydrazinobenzene-1-sulfonamide hydrochloride 
• 4392-54-5 4-aminosulfonylphenylhydrazine 
• 122259-14-7 4-{N'-[(E)-1-(4-Methoxy-phenyl)-3-phenyl-prop-2-en-(E)-ylidene]-hydrazino}-benzenesulfonamide 

Downstream Products

• 122259-25-0 C₂₉H₃₂N₄O₄S 
• 122288-21-5 C₂₉H₃₂N₄O₃S₂ 
• 122259-21-6 4-[4-Bromo-3-(4-methoxy-phenyl)-5-phenyl-pyrazol-1-yl]-benzenesulfonamide 
• 122288-23-7 C₂₆H₂₄N₄O₃S₂ 
• 122259-41-0 C₂₆H₂₆N₄O₄S 
• 122259-42-1 C₂₇H₂₈N₄O₄S 
• 122288-22-6 C₂₉H₂₄N₄O₄S 
• 122259-46-5 C₂₉H₂₄N₄O₃S₂ 
• 122259-53-4 N-[3-Allyl-4-oxo-thiazolidin-(2E)-ylidene]-4-[3-(4-methoxy-phenyl)-5-phenyl-pyrazol-1-yl]-benzenesulfonamide 
• 122288-24-8 N-[3-Allyl-4-oxo-[1,3]thiazinan-(2E)-ylidene]-4-[3-(4-methoxy-phenyl)-5-phenyl-pyrazol-1-yl]-benzenesulfonamide 
• 122259-47-6 C₃₀H₂₆N₄O₃S₂ 
• 122259-45-4 C₂₉H₃₀N₄O₃S₂ 
• 122259-54-5 4-[3-(4-Methoxy-phenyl)-5-phenyl-pyrazol-1-yl]-N-[4-oxo-3-phenyl-thiazolidin-(2E)-ylidene]-benzenesulfonamide 
• 122259-55-6 N-[3-Benzyl-4-oxo-thiazolidin-(2E)-ylidene]-4-[3-(4-methoxy-phenyl)-5-phenyl-pyrazol-1-yl]-benzenesulfonamide 

Relevant articles and documents

Synthesis of sulfonamides bearing 1,3,5-triarylpyrazoline and 4-thiazolidinone moieties as novel antimicrobial agents

Two series of sulfonamides were synthesized from 4-hydrazinylben-zenesulfonamide as the key starting material. 1,3,5-Triarylpyrazoline sulfonamides (2a-i) were obtained by cyclocondensation of various chalcones in 53-64 % yields, while 4-thiazolidinone derivatives (4a-e) were synthesized by cyclocondensation between mercaptoacetic acid and different phenylhydrazones in 43-62 % yields. The synthesized compounds were characterized based on FTIR, 1H-NMR, 13C-NMR and HRMS data. The sulfonamides were evaluated for their in vitro antimicrobial activities against four bacterial strains (E. coli, P. aeruginosa, B. subtillis and S aureus), two filamentous fungal strains (A. Niger and F. oxysporum) and two yeast strains (C. albicans and S. cerevisiae). Seven pyrazolines, 2a-c and 2e-h, exhibited significant inhibition of different microbial strains. Among them, compound 2b displayed good antifungal activity against A. Niger (MIC value at 12.5 μg mL-1) over the reference drug.

Synthesis, molecular docking study, and cytotoxic activity of 1,3,5-triaryl pyrazole derivatives

Synthesis, molecular docking study, and cytotoxic activity of a new group of 1,3,5-triaryl pyrazole derivatives were be studied. The antiproliferative activity of the final compounds were examined in MCF-7, AGS, HT-29 and NIH3T3 cell lines by MTT assay, u

Trisubstituted pyrazoles of possible antidiabetic and antibacterial activity

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