80887-01-0

Basic information

• Product Name: Benzoyl chloride, 2-bromo-5-nitro-
• Synonyms: 2-bromo-5-nitro-benzoyl chloride;2-Brom-5-nitro-benzoylchlorid;2-bromo-5-nitrobenzoylchloride;2-bromo-5-nitrobenzoic acid;2-bromo-5-nitrobenzoic acid chloride;3-nitro-6-bromo-benzoylchloride
• CAS NO: 80887-01-0
• Molecular Formula: C7H3BrClNO3
• Molecular Weight: 264.463
• Mol File: 80887-01-0.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: Benzoyl chloride, 2-bromo-5-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoyl chloride, 2-bromo-5-nitro-(80887-01-0)
• EPA Substance Registry System: Benzoyl chloride, 2-bromo-5-nitro-(80887-01-0)

Safety Data

• Hazardous Substances Data: 80887-01-0(Hazardous Substances Data)

Upstream product

• 943-14-6 2-bromo-5-nitrobenzoic acid 
• 79-37-8 oxalyl dichloride 

Downstream Products

• 654083-85-9 C₁₄H₁₃BrN₂O₃S 
• 332369-06-9 4-[2,4-bis-(2-bromo-4-nitrobenzoylamino)phenoxy]phthalic acid dimethyl ester 
• 711010-39-8 8-Amino-5-ethyl-5H-Phenanthridin-6-one 
• 373622-95-8 2-bromo-N-methoxy-N-methyl-5-nitrobenzamide 
• 84459-32-5 2-bromo-5-nitrobenzaldehyde 
• 1037082-29-3 tert-butyl (2-bromo-5-nitrobenzyl)(methyl)carbamate 
• 1037082-28-2 1-(2-bromo-5-nitrophenyl)-N-methylmethanamine 

Relevant articles and documents

Synthesis of Methoxy-, Methylenedioxy-, Hydroxy-, and Halo-Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Inhibitors and Their Biological Activity for Drug-Resistant Cancer

As a recently discovered DNA repair enzyme, tyrosyl-DNA phosphodiesterase 1 (TDP1) removes topoisomerase IB (TOP1)-mediated DNA protein cross-links. Inhibiting TDP1 can potentiate the cytotoxicity of TOP1 inhibitors and overcome cancer cell resistance to

Utilization of BozPhos as an Effective Ligand in Enantioselective C-H Functionalization of Cyclopropanes: Synthesis of Dihydroisoquinolones and Dihydroquinolones

The bisphosphine monoxide (R,R)-BozPhos enables enantioselective C-H functionalization of cyclopropanes in a palladium-catalyzed cyclization. The synthesis of a broad spectrum of dihydroisoquinolones and dihydroquinolones in good yields and high enantiomeric excess was achieved through the use of this hemilabile ligand. Furthermore, the isolation of an intermediary palladium(II)-BozPhos complex after oxidative addition was successful and a second complex provided further insight into bond length and angles through a crystal structure.

Discovery of a Highly Potent, Selective, and Orally Bioavailable Macrocyclic Inhibitor of Blood Coagulation Factor VIIa-Tissue Factor Complex

Inhibitors of the tissue factor (TF)/factor VIIa complex (TF-FVIIa) are promising novel anticoagulants which show excellent efficacy and minimal bleeding in preclinical models. Starting with an aminoisoquinoline P1-based macrocyclic inhibitor, optimizatio