80930-39-8Relevant articles and documents
Imidazolyl Derivatives of The Chroman Ring. 1.
Cozzi, Paolo,Mongelli, Nicola,Pillan, Antonio
, p. 311 - 315 (2007/10/02)
The synthesis of 2-(1H-imidazol-1-yl)-2,3-dihydro-2H-1-benzopyran-4-ones (I) through 3-bromo-2,3-dihydro-4H-1-benzopyran-4-ones or more conveniently through chroman ring closure from 2-(1H-imidazol-1-yl)-2'-hydroxy-acetophenones is described.The ring closure also works well for the pyrazolyl derivatives.Compounds I and the corresponding imidazolylchromanols, -chromenes, and -chromans derived from the former, were pharmacologically investigated.