81010-23-3 Usage
Description
(3S,7R,11Z)-14,16-dihydroxy-3-methyl-1-oxo-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-7-yl acetate is a complex organic molecule characterized by a 14-membered carbon ring. It features two hydroxyl groups, an acetate group, a methyl group, and a keto group. (3S,7R,11Z)-14,16-dihydroxy-3-methyl-1-oxo-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-7-yl acetate is a derivative of 2-benzoxacyclotetradecin, which is a heterocyclic compound. Its intricate structure suggests potential applications in medicinal chemistry, pharmaceuticals, or as a precursor for synthesizing other organic compounds. Further research is required to ascertain its specific properties, uses, and possible biological activity.
Uses
Used in Medicinal Chemistry:
(3S,7R,11Z)-14,16-dihydroxy-3-methyl-1-oxo-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-7-yl acetate is used as a compound of interest in medicinal chemistry for its potential to be developed into pharmaceutical agents. Its unique structure may allow for the modulation of biological targets and pathways, offering new avenues for therapeutic intervention.
Used in Pharmaceutical Development:
In the pharmaceutical industry, (3S,7R,11Z)-14,16-dihydroxy-3-methyl-1-oxo-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-7-yl acetate is used as a starting material for the synthesis of new drugs. Its complex molecular architecture could be leveraged to create novel therapeutic agents with specific mechanisms of action.
Used in Organic Synthesis:
(3S,7R,11Z)-14,16-dihydroxy-3-methyl-1-oxo-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-7-yl acetate is utilized as a key intermediate in organic synthesis. Its functional groups and ring system provide a foundation for creating a variety of complex organic molecules with diverse applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 81010-23-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,0,1 and 0 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 81010-23:
(7*8)+(6*1)+(5*0)+(4*1)+(3*0)+(2*2)+(1*3)=73
73 % 10 = 3
So 81010-23-3 is a valid CAS Registry Number.
81010-23-3Relevant articles and documents
Correlation of the absolute conformation of sec alcohols derived from macrocyclic lactones of resorcylic acid and their stereoselective transacetylation in organic solvents by Pseudomonas fluorescens lipase
Gelo-Pujic,Antolic,Kojic-Prodic,Sunjic
, p. 13753 - 13764 (2007/10/02)
Transacetylation of diastereomeric pairs of sec. alcohols, derived from macrocyclic lactones of resorcylic acid; 7α,β-trans-zearalenols (1,2, full names; (3S,7R and 3S,7S) trans-3,4,5,6,9,10-octahydro-7,14,16-trihydroxy-3-methyl-1H-2-benzoxac yclotetradecine-1-ones), 7α,β-cis-zearalenols (5,6), and 7α,β-zearanols (9,10, full names; (3S,7R and 3S,7S)3,4,5,6,9,10,11,12-decahydro-7,14,16-trihydroxy-3-methyl-1H-2-be nzoxacyclotetradecine-1-ones) by vinylacetate, catalyzed by Pseudomonas sp. and Pseudomonas fluorescens lipase in n-heptane and acetonitrile has been studied. It is highly stereoselective; diastereomeric excess of 7β-O-acetates was usually near 100%. K(M), V(max) and specificity constant V(max)/K(M) do not significantly differ for 7β-stereoisomers 2, 6 and 10. However, they notably change on going from n-heptane to acetonitrile, and the specificity constant drops by factor ca 10-100. The enzyme-bound water is assumed to be partly released in the latter solvent, thus diminishing the interaction with the hydrophilic region of the substrates, and affecting the activity, but not the stereoselectivity of lipases. To correlate the structural and conformational properties of these substrates with unexpectedly high diastereoselectivity of enzymatic transacetylation, the solid state structures of 7β-isomers 2, 4, 6, 10 and 12 have been determined by X-ray analysis. The X-ray structure analysis has revealed that the 7α and 7β isomers possess notably different and in some cases almost mirror-image related absolute conformations around the reactive center. The importance of conformational chirality in the hydrophobic region of these substrates for stereoselection in transacylation by microbial lipases is discussed.
