81028-69-5 Usage
General Description
4-Phenoxythiophene-2-carboxylic acid is a heterocyclic compound with a molecular formula C12H8O3S. It is derived from thiophene, and its structure contains a thiophene ring with a carboxylic acid and a phenoxy group attached to it. 4-Phenoxythiophene-2-carboxylic acid is used as a building block in the synthesis of pharmaceuticals and agrochemicals due to its ability to act as a ligand or chelating agent in coordination chemistry. It is also used in research and development of materials science and organic chemistry due to its interesting chemical and physical properties.
Check Digit Verification of cas no
The CAS Registry Mumber 81028-69-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,0,2 and 8 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 81028-69:
(7*8)+(6*1)+(5*0)+(4*2)+(3*8)+(2*6)+(1*9)=115
115 % 10 = 5
So 81028-69-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H8O3S/c12-11(13)10-6-9(7-15-10)14-8-4-2-1-3-5-8/h1-7H,(H,12,13)
81028-69-5Relevant articles and documents
Application of Regioselective Thiophene Lithiation to the Synthesis of Thiophene Analogues of Xanthones and Thioxanthones
Watthey, Jeffrey W.,Desai, Mahesh
, p. 1755 - 1759 (2007/10/02)
Treatment of 3-(p-tolyloxy)thiophene (3) with phenyllithium followed by carbonation with CO2 was found to be a convenient procedure for the preparation of the thiophene-2-carboxylic acid 4, which was cyclized to 5 with PPE.Treatment of 3 with butyllithium followed by carbonation gave the thiophene-2,5-dicarboxylic acid 8 which was cyclized to 9.Alkaline permanganate oxidation of 4 gave the diacid 10, which was cyclized to the tricyclic acid 11.Similar lithiation reactions were observed with additional 3-(aryloxy)thiophenes and with 3-(arylthio)thiophenes, and xanthone analogues were prepared from the resulting intermediates.
