81096-49-3

Basic information

• Product Name: 2-(cyclohex-1-en-1-yl)-1-phenylpropan-1-one
• Synonyms: 2-(cyclohex-1-en-1-yl)-1-phenylpropan-1-one
• CAS NO: 81096-49-3
• Molecular Weight: 214.307
• Mol File: 81096-49-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(cyclohex-1-en-1-yl)-1-phenylpropan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(cyclohex-1-en-1-yl)-1-phenylpropan-1-one(81096-49-3)
• EPA Substance Registry System: 2-(cyclohex-1-en-1-yl)-1-phenylpropan-1-one(81096-49-3)

Safety Data

• Hazardous Substances Data: 81096-49-3(Hazardous Substances Data)

Upstream product

• 28075-50-5 cyclohex-1-en-1-yl trifluoromethane sulfonate 
• 93-55-0 1-phenyl-propan-1-one 
• 98-86-2 acetophenone 
• 80385-43-9 2-cyclohexylideneacetyl chloride 
• 84189-13-9 cyclohexene-1-acetyl chloride 
• 1017-23-8 2-(cyclohex-1-en-1-yl)-1-phenylethan-1-one 

Relevant articles and documents

Method for synthesizing polysubstituted alpha, beta unsaturated ketones

The invention particularly relates to a method for synthesizing polysubstituted alpha, beta unsaturated ketones. The method comprises the following steps: 1, adding Ni(cod), an N-heterocyclic carbene ligand, Cs2CO3 and a beta, gamma unsaturated ketone into a non-polar aprotic organic solvent, and mixing to obtain a mixture; 2, adding the mixture obtained in the step 1 into a dried container, reacting for 10-40 hours at the reaction temperature of 120-180 DEG C, and cooling to room temperature after the reaction is finished, so as to obtain a crude product; 3, purifying. According to the method, cheap Ni(cod) is adopted as a catalyst, carbon-carbon bonds are activated by a transition metal, power is provided for the reaction through isomerization of double bonds, the synthesis methodis simple, the substrates are stable and cheap, the reaction is less limited by the substrate, and the substrates are wide in application range.

Palladium-catalyzed alkenylation of ketone enolates under mild conditions

A protocol for a mild, catalytic, intermolecular alkenylation of ketone enolates has been developed using a Pd/Q-Phos catalyst. Efficient intermolecular coupling of a variety of ketones with alkenyl bromides was achieved with a slight excess of LiHMDS and temperatures down to 0 °C.