81112-84-7

Basic information

• Product Name: 5-(1-hydroxy-3-phenylpropyl)furan-2(5H)-one
• Synonyms: 5-(1-hydroxy-3-phenylpropyl)furan-2(5H)-one
• CAS NO: 81112-84-7
• Molecular Weight: 218.252
• Mol File: 81112-84-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-(1-hydroxy-3-phenylpropyl)furan-2(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(1-hydroxy-3-phenylpropyl)furan-2(5H)-one(81112-84-7)
• EPA Substance Registry System: 5-(1-hydroxy-3-phenylpropyl)furan-2(5H)-one(81112-84-7)

Safety Data

• Hazardous Substances Data: 81112-84-7(Hazardous Substances Data)

Upstream product

• 104-53-0 3-phenyl-propionaldehyde 
• 61550-02-5 (furan-2-yloxy)-trimethylsilane 

Downstream Products

• 343953-27-5 5-[3-Phenyl-prop-(E)-ylidene]-5H-furan-2-one 

Relevant articles and documents

Asymmetric vinylogous aldol reaction of silyloxy furans with a chiral organic salt

Despite their synthetic significance there is a general lack of asymmetric vinylogous aldol reactions that tolerate variations of both the silyloxy furans and aldehydes. We have developed a new chiral organic catalyst based on a carboxylate-ammonium salt prepared from a thiourea-amine and a carboxylic acid. This new catalyst enabled us to develop an efficient asymmetric vinylogous aldol reaction of unprecedented scope with respect to both 2-trimethylsilyloxy furans and aldehydes.

SYNTHESIS OF 4-YLIDENEBUTENOLIDES FROM 2-TRIMETHYLSILOXYFURAN

Dehydration or dealkoxylation of the reaction products of various aldehydes, ketones, and acetals with 2-trimethylsiloxyfuran gave corresponding 4-ylidenebutenolides in good to high overall yields.