81136-10-9

Basic information

• Product Name: 2-chloro-3-phenylpropanoic acid chloride
• CAS NO: 81136-10-9
• Molecular Weight: 203.068
• Mol File: 81136-10-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-chloro-3-phenylpropanoic acid chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-3-phenylpropanoic acid chloride(81136-10-9)
• EPA Substance Registry System: 2-chloro-3-phenylpropanoic acid chloride(81136-10-9)

Safety Data

• Hazardous Substances Data: 81136-10-9(Hazardous Substances Data)

Upstream product

• 828-01-3 phenyllactic acid 
• 16503-53-0 2-bromo-3-phenylpropanoic acid 
• 150-30-1 Phenylalanine 
• 501-52-0 3-Phenylpropionic acid 
• 7474-06-8 2-chloro-3-phenylpropionic acid 
• 27172-85-6 phenylalanine methyl ester hydrochloride 
• 4530-18-1 2-(tert-butoxycarbonylamino)-3-phenylpropionic acid 

Downstream Products

• 20334-86-5 N-phenyl-2-chloro-3-phenylpropanamide 
• 6632-27-5 2-chloro-N-(3-nitrophenyl)-3-phenylpropanamide 
• 1570275-31-8 2-benzyl-N,N,4,4-tetraphenylbutanamide 
• 1570274-33-7 2-chloro-N,N,3-triphenylpropanamide 
• 1330781-99-1 6-(5-methyl-1H-pyrazol-4-yl)-2-(2-phenyl-1-pyrrolidin-1-ylethyl)thieno[3,2-d]pyrimidin-4(3H)-one 
• 90560-55-7 DL-N-Brom-α-chlor-hydrozimtsaeure-amid 
• 90004-75-4 DL-1-Chlor-1-brom-2-phenyl-ethan 
• 141734-77-2 (7R)-methyl 7-benzyl 1,3,4,5,6,7-hexahydro-6-oxopyrrolo<4,3,2-fg><3>benzazocine-4-carboxylate 
• 141734-77-2 (7S)-methyl 7-benzyl 1,3,4,5,6,7-hexahydro-6-oxopyrrolo<4,3,2-fg><3>benzazocine-4-carboxylate 
• 18166-56-8 α-chloro-β-phenylpropionamide 
• 117770-84-0 N-(2-chloro-3-phenylpropionyl)tryptophan methyl ester 
• 87968-04-5 2-chloro-N,N-dimethyl-3-phenylpropanamide 
• 7474-06-8 2-chloro-3-phenylpropionic acid 

Relevant articles and documents

Synthesis and anti-parasitic activity of C-benzylated (N-arylcarbamoyl)alkylphosphonate esters

Unexpected substituent-dependent regioselectivty challenges in the synthesis of C-benzylated (N-arylcarbamoyl)phosphonate esters have been resolved. The C-benzylated N-furfurylcarbamoyl derivative showed low micromolar PfLDH inhibition, while one of the C-benzylated N-arylcarbamoyl analogues was active against Nagana Trypanosoma brucei parasites which are responsible for African trypanosomiasis in cattle.

Highly stereoselective synthesis of α-alkyl-α-hydroxycarboxylic acid derivatives catalyzed by a dinuclear zinc complex

A dinuclear zinc-ProPhenol catalyst enables highly enantioselective nitro-Michael reactions with oxazol-4(5H)-ones as nucleophilic substrates (see scheme, Nap=2-naphthyl). This work highlights the utility of the ProPhenol family of ligands. The modular nature of these ligands proved crucial in the optimization of reaction conditions to achieve excellent stereoselectivities. Copyright