81154-34-9

Basic information

• Product Name: 3-(p-anisyl)-1,2,4-triazolo<3,4-c>pyrimido<4,5-b>tetrahydrobenzothiophene
• Synonyms: 3-(p-anisyl)-1,2,4-triazolo<3,4-c>pyrimido<4,5-b>tetrahydrobenzothiophene
• CAS NO: 81154-34-9
• Molecular Weight: 336.417
• Mol File: 81154-34-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(p-anisyl)-1,2,4-triazolo<3,4-c>pyrimido<4,5-b>tetrahydrobenzothiophene(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(p-anisyl)-1,2,4-triazolo<3,4-c>pyrimido<4,5-b>tetrahydrobenzothiophene(81154-34-9)
• EPA Substance Registry System: 3-(p-anisyl)-1,2,4-triazolo<3,4-c>pyrimido<4,5-b>tetrahydrobenzothiophene(81154-34-9)

Safety Data

• Hazardous Substances Data: 81154-34-9(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 40106-45-4 4-hydrazino-5,6-tetramethylenothieno<2,3-d>pyrimidine 
• 81154-30-5 4-methoxy-benzaldehyde (5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl)hydrazone 

Relevant articles and documents

Simple oxidation of pyrimidinylhydrazones to triazolopyrimidines and their inhibition of Shiga toxin trafficking

The oxidative cyclisation of a range of benzothieno[2,3-d]pyrimidine hydrazones (7a-j) to the 1,2,4-triazolo[4,3-c]pyrimidines (8a-j) catalysed by lithium iodide or to the 1,2,4-triazolo[1,5-c]pyrimidines (10a-j) with sodium carbonate is presented. A complementary synthesis of the 1,2,4-triazolo[1,5-c]pyrimidines starting from the amino imine 11 is also reported. The effect of these compounds on Shiga toxin (STx) trafficking in HeLa cells and comparison to the previously reported Exo2 is also detailed.