81170-13-0 Usage
Derivative of phenylpropionic acid
It is a derivative of phenylpropionic acid This compound is derived from phenylpropionic acid, with modifications to its structure.
Fluorine atom attachment
A fluorine atom is attached to the phenyl ring The presence of the fluorine atom in the compound enhances its reactivity and properties.
Usage in synthesis
Used in the synthesis of various pharmaceuticals and agrochemicals This compound serves as a starting material or building block in the production of different drugs and agrochemicals.
Potential applications in organic chemistry
It has potential applications in the field of organic chemistry Researchers are exploring its use in organic synthesis and reactions for new compounds and applications.
Physical state and appearance
White crystalline solid at room temperature The compound forms a white crystalline solid under normal conditions, which is a desirable property for handling and processing.
Solubility
Soluble in water and organic solvents 2-(4-Fluorophenyl)-2-hydroxypropionic acid can dissolve in both water and various organic solvents, making it suitable for a wide range of applications and reactions.
Valuable building block
A valuable building block for the production of a wide range of compounds with important biological and industrial applications This compound is a versatile intermediate that can be used to create many other important compounds for various industries and research areas.
Check Digit Verification of cas no
The CAS Registry Mumber 81170-13-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,1,7 and 0 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 81170-13:
(7*8)+(6*1)+(5*1)+(4*7)+(3*0)+(2*1)+(1*3)=100
100 % 10 = 0
So 81170-13-0 is a valid CAS Registry Number.
81170-13-0Relevant articles and documents
Stereospecific decarboxylative allylation of sulfones
Weaver, Jimmie D.,Ka, Being J.,Morris, David K.,Thompson, Ward,Tunge, Jon A.
supporting information; scheme or table, p. 12179 - 12181 (2010/10/03)
Allyl sulfonylacetic esters undergo highly stereospecific, palladium-catalyzed decarboxylative allylation. The reaction allows the stereospecific formation of tertiary homoallylic sulfones in high yield. In contrast to related reactions that proceed at -100 °C and require highly basic preformed organometallics, the decarboxylative coupling described herein occurs under mild nonbasic conditions and requires no stoichiometric additives. Allylation of the intermediate α-sulfonyl anion is more rapid than racemization, leading to a highly enantiospecific process. Density functional theory calculations indicate that the barrier for racemization is 9.9 kcal/mol, so the barrier for allylation must be 9.9 kcal/mol.
