81206-82-8

Basic information

• Product Name: 1-methylidene-(4-trifluoromethyl)cyclohexane
• Synonyms: 1-methylidene-(4-trifluoromethyl)cyclohexane
• CAS NO: 81206-82-8
• Molecular Weight: 164.171
• Mol File: 81206-82-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-methylidene-(4-trifluoromethyl)cyclohexane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methylidene-(4-trifluoromethyl)cyclohexane(81206-82-8)
• EPA Substance Registry System: 1-methylidene-(4-trifluoromethyl)cyclohexane(81206-82-8)

Safety Data

• Hazardous Substances Data: 81206-82-8(Hazardous Substances Data)

Upstream product

• 81206-65-7 4-(trifluoromethyl)-1-<(trimethylsilyl)methyl>cyclohex-1-ene 
• 70901-64-3 trimethyl(2-methylenebut-3-enyl)silane 

Relevant articles and documents

Diels-Alder Reactions of (Trifluoromethyl)ethene and (Trifluoromethyl)styrenes with Functionalized Butadiens

The-Alder reactions of (trifluoromethyl)ethene (1) with 2-(trimethylsiloxy)buta-1,3-diene (2), 2--1,3-butadiene (4), and 1-methoxy-3-(trimethylsiloxy)buta-1,3-diene (6) were carried out to give the corresponding cycloadducts in 17-38percent yields.It was found that the former two cycloadducts were a mixture of para (major) and meta (minor) isomers, while the latter was the para isomer exlusively.Similary, β-(trifluoromethyl)-4-(methoxycarbonyl)styrene (9) and β-(trifluoromethyl)-4-nitrostyrene (10) were allowed to react with 4 and 6, giving the corresponding cycloadducts in 56-90percent yields.The regioselectivity of the reaction on using 6 as the diene turned out to be extremely high, leading to the formation of only one regioisomer.The substituent effect of the trifluoromethyl group in the Diels-Alder reaction in terms of regioselectivity is discussed.