81310-56-7 Usage
General Description
1-(Piperidin-3-ylmethyl)piperidine, also known as 3-(Piperidin-1-ylmethyl)piperidine, is a chemical compound with the molecular formula C11H22N2. It is a piperidine derivative with two piperidine rings, one of which is substituted with a piperidin-3-ylmethyl group. 1-(PIPERIDIN-3-YLMETHYL)PIPERIDINE is commonly used in the synthesis of pharmaceuticals and agrochemicals, and it may also have potential applications in organic synthesis and material chemistry. The exact properties and uses of 1-(Piperidin-3-ylmethyl)piperidine may vary depending on the specific application, and further research and testing may be necessary to fully understand its potential uses and effects.
Check Digit Verification of cas no
The CAS Registry Mumber 81310-56-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,3,1 and 0 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 81310-56:
(7*8)+(6*1)+(5*3)+(4*1)+(3*0)+(2*5)+(1*6)=97
97 % 10 = 7
So 81310-56-7 is a valid CAS Registry Number.
InChI:InChI=1/C11H22N2/c1-2-7-13(8-3-1)10-11-5-4-6-12-9-11/h11-12H,1-10H2
81310-56-7Relevant articles and documents
Design and synthesis of a hybrid series of potent and selective agonists of α7 nicotinic acetylcholine receptor
Nencini, Arianna,Castaldo, Cristiana,Comery, Thomas A.,Dunlop, John,Genesio, Eva,Ghiron, Chiara,Haydar, Simon,Maccari, Laura,Micco, Iolanda,Turlizzi, Elisa,Zanaletti, Riccardo,Zhang, Jean
, p. 401 - 418 (2014)
α7 nicotinic acetylcholine receptor agonists are promising therapeutic candidates for the treatment of cognitive impairment. As a follow up of our internal medicinal chemistry program we investigated a novel series of α7 nAChR agonists. Starting from molecular docking studies on two series of molecules recently developed in our laboratories, an alternative scaffold was designed attempting to combine the optimal features of these previously identified urea and pyrazole compounds. Based on our previous SAR knowledge and on predicted drug-like properties, a small library was synthesized in parallel manner, affording compounds with excellent α7 nAChR activity, selectivity and preliminary ADME profile.