81327-24-4

Basic information

• Product Name: 2-(3-Bromo-1-oxy-quinolin-2-yl)-1-phenyl-ethanone
• CAS NO: 81327-24-4
• Molecular Weight: 342.192
• Mol File: 81327-24-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(3-Bromo-1-oxy-quinolin-2-yl)-1-phenyl-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-Bromo-1-oxy-quinolin-2-yl)-1-phenyl-ethanone(81327-24-4)
• EPA Substance Registry System: 2-(3-Bromo-1-oxy-quinolin-2-yl)-1-phenyl-ethanone(81327-24-4)

Safety Data

• Hazardous Substances Data: 81327-24-4(Hazardous Substances Data)

Upstream product

• 22615-00-5 3-bromoquinoline N-oxide 
• 98-86-2 acetophenone 

Relevant articles and documents

NUCLEOPHILIC SUBSTITUTION OF 4-CHLOROQUINOLINE 1-OXIDE AND RELATED COMPOUNDS BY MEANS OF HYDRIDE ELIMINATION

The reaction of 4-chloroquinoline 1-oxide (1) with pinacolone and t-BuOK in t-BuNH2 at -10 ca. -15 deg C gives 4-chloro-2-pinacolylquinoline 1-oxide in good yield by means of hydride-elimination.Similar reactions of 1 with acetone, 2-butanone, acetophenone, and ethyl and t-butyl acetates occur when treated with t-BuOK or n-BuLi in t-BuNH2 at -10 ca. -15 deg C, or t-BuOK, KNH2 or NaNH2 in liq NH3 at -70 deg C.Reactions of this type proceed also with quinoline 1-oxide (2), 3-bromoquinoline 1-oxide (3), p-chloronitrobenzene (4) and nitrobenzene.