81374-77-8

Basic information

• Product Name: 2-(1-Hydroxy-1,1-diphenylethyl)pyridine N-oxide
• Synonyms: 2-(1-Hydroxy-1,1-diphenylethyl)pyridine N-oxide
• CAS NO: 81374-77-8
• Molecular Weight: 291.349
• Mol File: 81374-77-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(1-Hydroxy-1,1-diphenylethyl)pyridine N-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-Hydroxy-1,1-diphenylethyl)pyridine N-oxide(81374-77-8)
• EPA Substance Registry System: 2-(1-Hydroxy-1,1-diphenylethyl)pyridine N-oxide(81374-77-8)

Safety Data

• Hazardous Substances Data: 81374-77-8(Hazardous Substances Data)

Upstream product

• 119-61-9 benzophenone 
• 931-19-1 2-methylpyridine N-oxide 

Downstream Products

• 1748-99-8 2-(1-Hydroxy-1,1-diphenylethyl)pyridine 

Relevant articles and documents

DIPHENYLHYDROXYMETHYLATION OF 2-METHYLPYRIDINE N-OXIDE BY KETYLS AND DIANIONS OF BENZOPHENONE

In the reaction of 2-methylpyridine N-oxide with the lithium ketyl and the dianion of benzophenone the products from diphenylhydroxymethylation in the side chain, i.e., 2-(1-hydroxy-1,1-diphenylethyl)pyridine N-oxide, and in the ring, i.e., 2-methyl-6-(diphenylhydroxymethyl)pyridine N-oxide, are formed.The product from reductive diphenylhydroxymethylation in the methyl group, i.e., 2-(1-hydroxy-1,1-diphenylethyl)pyridine, is formed preferentially in the reactions with the ketyl and the dianion of benzophenone.The condensation with the sodium ketyl and the dianion of benzophenone takes place similarly and leads to significantly lower yields of the products.