81438-60-0 Usage
General Description
2-METHYL-6-NITRO-IMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER is a chemical compound with the molecular formula C11H10N4O4. It is an ethyl ester of the carboxylic acid derivative, and it contains a nitro group and a methyl group attached to an imidazo[1,2-a]pyridine-3-carboxylic acid structure. 2-METHYL-6-NITRO-IMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER has potential pharmaceutical applications, particularly in the development of new drugs, due to its unique chemical structure and properties. 2-METHYL-6-NITRO-IMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER may be used as a precursor in the synthesis of other organic compounds and can serve as a valuable tool for research in chemical and pharmaceutical sciences.
Check Digit Verification of cas no
The CAS Registry Mumber 81438-60-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,4,3 and 8 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 81438-60:
(7*8)+(6*1)+(5*4)+(4*3)+(3*8)+(2*6)+(1*0)=130
130 % 10 = 0
So 81438-60-0 is a valid CAS Registry Number.
81438-60-0Relevant articles and documents
Design, synthesis and biological activity of N-(2-phenoxy)ethyl imidazo[1,2-a]pyridine-3-carboxamides as new antitubercular agents
Wang, Apeng,Lv, Kai,Li, Linhu,Liu, Hongtao,Tao, Zeyu,Wang, Bin,Liu, Mingliang,Ma, Chao,Ma, Xican,Han, Bing,Wang, Aoyu,Lu, Yu
, p. 715 - 725 (2019/06/24)
A series of N-(2-phenoxy)ethyl imidazo[1,2-a]pyridine-3-carboxamides (IPAs), based on the structure of WZY02 discovered in our lab, were designed and synthesized as new anti-TB agents. Results reveal that many of them exhibit excellent in vitro inhibitory activity with low nanomolar MIC values against both drug-sensitive MTB strain H37Rv and drug-resistant clinical isolates. Compounds 15b and 15d display good safety and pharmacokinetic profiles, suggesting their promising potential to be lead compounds for future antitubercular drug discovery.
Research on heterocyclic compounds. XII. Preparation and antiinflammatory activity of 2-methylimidazo [1,2-a]pyridine-3-carboxylic acids
Abignente,Arena,de Caprariis,Luraschi,Marmo,Lampa,Vairo,Somma
, p. 22 - 35 (2007/10/02)
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