81477-54-5Relevant articles and documents
Further Studies on the Synthesis of Thienamycin: a Facile and Stereoselective Synthesis of a Bicyclic β-Keto Ester by 1,3-Dipolar Cycloaddition
Kametani, Tetsuji,Huang, Shyh-Pyng,Nakayama, Atsushi,Honda, Toshio
, p. 2328 - 2331 (1982)
A potential compound, ethyl 6-*)-1-hydroxyethyl>-3,7-dioxo-1-azabicycloheptane-2-carboxylate (18), for the synthesis of thienamycin (1), was stereoselectively prepared by 1,3-dipolar cycloaddition of the nitrone (12) and benzyl crotonate as a key reaction.