81518-74-3Relevant articles and documents
Synthesis and evaluation of novel, selective, functionalized γ-butyrolactones as sigma-2 ligands
Blass, Benjamin E.,Blattner, Kevin M.,Canney, Daniel J.,Gao, Rong,Gordon, John C.,Pippin, Douglas A.
, p. 337 - 349 (2022/01/19)
The sigma-2 (σ2) receptor was discovered nearly 40 years ago and was recently identified as the Transmembrane Protein 97 (TMEM97, also known as MAC30 (Meningioma-associated protein)). Aberrant σ2 activity has been linked to diseases
Nickel-Catalyzed Hydrosilylation of Terminal Alkenes with Primary Silanes via Electrophilic Silicon-Hydrogen Bond Activation
Wu, Xiaoyu,Ding, Guangni,Lu, Wenkui,Yang, Liqun,Wang, Jingyang,Zhang, Yuxuan,Xie, Xiaomin,Zhang, Zhaoguo
, p. 1434 - 1439 (2021/02/16)
We report a simple and effective nickel-based catalytic system, NiCl2·6H2O/tBuOK, for the electrophilically activated hydrosilylation of terminal alkenes with primary silanes. This protocol provides excellent performance under mild reaction conditions: ex
Highly Regioselective Copper-Catalyzed Transfer Hydrodeuteration of Unactivated Terminal Alkenes
Clark, Joseph R.,Reyes, Albert,Torres, Emanuel Rivera,Vang, Zoua Pa
supporting information, (2022/01/06)
Catalytic transfer hydrodeuteration of unactivated alkenes is challenging because of the requirement that chemically similar hydrogen and deuterium undergo selective insertion across a π-bond. We now report a highly regioselective catalytic transfer hydro