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81533-88-2

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81533-88-2 Usage

Description

1-((p-(2-(3-Chloro-6-methoxybenzenesulfonamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea, also known as TAK-242, is a chemical compound with potential anti-inflammatory properties. It is a small molecule inhibitor that targets the Toll-like receptor 4 (TLR4) signaling pathway, which plays a critical role in the body's immune response and inflammation.

Uses

Used in Pharmaceutical Industry:
TAK-242 is used as an anti-inflammatory agent for its ability to block TLR4-mediated inflammatory responses. This makes it a potential therapeutic option for conditions characterized by excessive inflammation, such as sepsis, rheumatoid arthritis, and other inflammatory diseases.
Used in Drug Development:
TAK-242 is used as a research compound in the development of new anti-inflammatory drugs. Its potential to modulate the TLR4 signaling pathway offers opportunities for creating novel treatments for a range of inflammatory conditions.
Used in Clinical Studies:
TAK-242 is used as a subject in preclinical and clinical studies to evaluate its efficacy and safety in treating various inflammatory conditions. These studies aim to determine the optimal dosage, administration methods, and potential side effects of TAK-242 as a therapeutic agent.

Check Digit Verification of cas no

The CAS Registry Mumber 81533-88-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,5,3 and 3 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 81533-88:
(7*8)+(6*1)+(5*5)+(4*3)+(3*3)+(2*8)+(1*8)=132
132 % 10 = 2
So 81533-88-2 is a valid CAS Registry Number.
InChI:InChI=1/C22H28ClN3O6S2/c1-32-20-12-9-17(23)15-21(20)34(30,31)24-14-13-16-7-10-19(11-8-16)33(28,29)26-22(27)25-18-5-3-2-4-6-18/h7-12,15,18,24H,2-6,13-14H2,1H3,(H2,25,26,27)

81533-88-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[4-[2-[(5-chloro-2-methoxyphenyl)sulfonylamino]ethyl]phenyl]sulfonyl-3-cyclohexylurea

1.2 Other means of identification

Product number -
Other names Urea,1-((p-(2-(3-chloro-6-methoxybenzenesulfonamido)ethyl)phenyl)sulfonyl)-3-cyclohexyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:81533-88-2 SDS

81533-88-2Downstream Products

81533-88-2Relevant articles and documents

Synthesis and pharmacological properties of sulfonylureas, isosters of glibenclamide

Fournier,Moreau,Narcisse,Choay

, p. 81 - 84 (2007/10/02)

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