81559-97-9

Basic information

• Product Name: (E)-1-(4-hydroxyphenyl)-5-morpholinopent-1-en-3-one hydrochloride
• Synonyms: (E)-1-(4-hydroxyphenyl)-5-morpholinopent-1-en-3-one hydrochloride
• CAS NO: 81559-97-9
• Molecular Weight: 297.782
• Mol File: 81559-97-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-1-(4-hydroxyphenyl)-5-morpholinopent-1-en-3-one hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-(4-hydroxyphenyl)-5-morpholinopent-1-en-3-one hydrochloride(81559-97-9)
• EPA Substance Registry System: (E)-1-(4-hydroxyphenyl)-5-morpholinopent-1-en-3-one hydrochloride(81559-97-9)

Safety Data

• Hazardous Substances Data: 81559-97-9(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 22214-30-8 (E)-4-(4-hydroxyphenyl)-3-buten-2-one 
• 123-08-0 4-hydroxy-benzaldehyde 
• 50-00-0 formaldehyd 

Relevant articles and documents

An efficient water-mediated synthetic route for the alkylation of heteroarenes

An efficient synthetic route has been described for the alkylation of 1H-indole, 1H-benzimidazole, and 1H-benzotriazole. This approach features the alkylation of heteroaromatics through in situ generated enones from ketonic Mannich bases under metal-free conditions. A series of alkylated heteroaromatics have been synthesized via the K10 catalyzed alkylation reactions of these heteroaromatics with a variety of ketonic Mannich bases. Environmentally benign K10 catalyst, water-mediated mild reaction conditions, and the efficient synthesis of alkylated products are the advantages of this alkylation method.

Mannich Bases of 4-Phenyl-3-buten-2-one: A New Class of Antiherpes Agent

The morpholine Mannich base of 4-phenyl-3-buten-2-one was found to have activity in model infections of herpes simplex.The activity was essentially equivalent to that of disodium phosphonoacetate.This paper presents the biological activity and synthesis o