815590-48-8

Basic information

• Product Name: 2-{1-[4-(4-methoxy-benzenesulfonyl)-piperazin-1-yl]-ethyl}-3H-quinazolin-4-one
• Synonyms: 2-{1-[4-(4-methoxy-benzenesulfonyl)-piperazin-1-yl]-ethyl}-3H-quinazolin-4-one
• CAS NO: 815590-48-8
• Molecular Weight: 428.512
• Mol File: 815590-48-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-{1-[4-(4-methoxy-benzenesulfonyl)-piperazin-1-yl]-ethyl}-3H-quinazolin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{1-[4-(4-methoxy-benzenesulfonyl)-piperazin-1-yl]-ethyl}-3H-quinazolin-4-one(815590-48-8)
• EPA Substance Registry System: 2-{1-[4-(4-methoxy-benzenesulfonyl)-piperazin-1-yl]-ethyl}-3H-quinazolin-4-one(815590-48-8)

Safety Data

• Hazardous Substances Data: 815590-48-8(Hazardous Substances Data)

Upstream product

• 144189-81-1 2-(1-bromoethyl)quinazolin-4(3H)-one 
• 121751-67-5 1‐(4‐methoxyphenylsulfonyl)piperazine 

Relevant articles and documents

PYRIMIDINE DERIVATIVES AS MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS

The present invention relates to compounds of Formula (I) as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.