81581-05-7

Basic information

• Product Name: 1-(4-Methoxy-benzyl)-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester
• Synonyms: 1-(4-Methoxy-benzyl)-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester;Ethyl 1-(4-Methoxybenzyl)-1H-1,2,3-triazole-4-carboxylate;Ethyl 1-[(4-Methoxyphenyl)Methyl]triazole-4-carboxylate;ethyl 1-[(4-methoxyphenyl)methyl]-1H-1,2,3-triazole-4-carboxylate
• CAS NO: 81581-05-7
• Molecular Formula: C₁₃H₁₅N₃O₃
• Molecular Weight: 261
• Mol File: 81581-05-7.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 1-(4-Methoxy-benzyl)-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Methoxy-benzyl)-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester(81581-05-7)
• EPA Substance Registry System: 1-(4-Methoxy-benzyl)-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester(81581-05-7)

Safety Data

• Hazardous Substances Data: 81581-05-7(Hazardous Substances Data)

Usage

General Description

1-(4-Methoxy-benzyl)-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester is an organic compound with the molecular formula C14H15N3O3. It is an ethyl ester derivative of 1-(4-Methoxy-benzyl)-1H-[1,2,3]triazole-4-carboxylic acid, which is a triazole derivative. Triazoles are a class of compounds with various pharmaceutical and agricultural applications, including as antifungal and anticancer agents. The addition of the ethyl ester moiety to the triazole compound can impact its chemical properties, such as solubility and stability, and may also affect its biological activity. The compound may have potential uses in medicinal chemistry and other fields where triazole derivatives are of interest.

Upstream product

• 70978-37-9 1-(azidomethyl)-4-methoxybenzene 
• 623-47-2 propynoic acid ethyl ester 
• 105-37-3 Ethyl propionate 

Downstream Products

• 716361-79-4 1-(4-methoxybenzyl)-1H-1,2,3-triazole-4-carboxylic acid 

Relevant articles and documents

4β-amidotriazole linked podophyllotoxin congeners: DNA topoisomerase-IIα inhibition and potential anticancer agents for prostate cancer

Topoisomerases (topo-I and topo-II) have occupied a significant role in DNA replication, transcription, and are a promising set of antitumor targets. In the present approach, a series of new 4β-amidotriazole linked podophyllotoxin derivatives (10a-i and 1

PYRAZOLE DERIVATIVES AS CYTOCHROME P450 INHIBITORS

The present invention provides compounds of formula (I), or pharmaceutically acceptable salts or solvates thereof, methods for their preparation, methods for their use, and pharmaceutical formulations comprising them.

Studies of v-Triazoles. Part 4. The 4-Methoxybenzyl Group, a Versatile N-Protecting Group for the Synthesis of N-Unsubstituted v-Triazoles

A series of readily prepared monocyclic N-(4-methoxybenzyl)-v-trizoles (1) have been converted into their N-unsubstituted derivatives (2) by treatment with trifluoroacetic acid at 65 deg C.The procedure allows the synthesis of a range of N-unsubstituted v