81616-17-3Relevant articles and documents
Degradative rearrangements of N-(t-butyloxycarbonyl)-O-methanesulfonyl- hydroxamic acids: A novel, reagent-based alternative to the Lossen rearrangement
Stafford, Jeffrey A.,Gonzales, Stephen S.,Barrett, David G.,Suh, Edward M.,Feldman, Paul L.
, p. 10040 - 10044 (2007/10/03)
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Amino-Protecting Reagents: New Promising Reagents for tert-Butoxycarbonylation, Benzyloxycarbonylation, and carbonylation
Kita, Yasuyuki,Haruta, Jun-ichi,Yasuda, Hitoshi,Fukunaga, Keiko,Shirouchi, Yoshiaki,Tamura, Yasumitsu
, p. 2697 - 2700 (2007/10/02)
A new method for the preparation of tert-butyl- (1d), benzyl- (1e), and (β-trimethylsilyl)ethyl α-methoxyvinyl carbonates (1f) has been devised.The reaction of these reagents with amino compounds proceeds rapidly under mild conditions to give the corresponding N-tert-butoxycarbonylated (N-Boc), N-benzyloxycarbonylated (N-Z), and N-carbonylated (N-Tmseoc) compounds in quantitative yields.Twenty-two examples using amines, amino alcohols, and amino acids were presented.