81616-75-3

Basic information

• Product Name: 2-methoxy-α-methylene-benzeneacetic acid
• Synonyms: 2-methoxy-α-methylene-benzeneacetic acid
• CAS NO: 81616-75-3
• Molecular Weight: 178.188
• Mol File: 81616-75-3.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 2-methoxy-α-methylene-benzeneacetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methoxy-α-methylene-benzeneacetic acid(81616-75-3)
• EPA Substance Registry System: 2-methoxy-α-methylene-benzeneacetic acid(81616-75-3)

Safety Data

• Hazardous Substances Data: 81616-75-3(Hazardous Substances Data)

Upstream product

• 93-25-4 2-methoxyphenylacetic acid 
• 27798-60-3 methyl 2-(2-methoxyphenyl)acetate 
• 54493-88-8 methyl 2-(2-methoxyphenyl)prop-2-enoate 
• 124-38-9 carbon dioxide 
• 767-91-9 1-ethynyl-2-methoxybenzene 
• 6056-23-1 ethyl (2-methoxyphenyl)acetate 
• 81616-76-4 2-(2-methoxyphenyl)propenoic acid ethyl ester 
• 579-74-8 2-Methoxyacetophenone 

Downstream Products

• 143392-21-6 3-(2-methoxyphenyl)furan-2(5H)-one 
• 96687-73-9 Methyl (S)-(+)-2-(2-methoxyphenyl)propanoate 
• 81616-80-0 (S)-2-(2-methoxyphenyl)-propionic acid 
• 1346947-73-6 C₂₁H₂₃NO₅S 
• 1346947-71-4 C₂₃H₂₁NO₄S 
• 1346947-69-0 C₁₉H₁₉NO₄S 
• 1346946-62-0 3-(2-(2-methoxyphenyl)acryloyl)oxazolidin-2-one 
• 133032-95-8 α-[[(2-amino phenyl)-thio]-methyl]-2-methoxy-benzeneacetic acid 
• 26767-06-6 2-(2-methoxyphenyl)-2-oxoacetic acid 
• 349552-88-1 2-(2-methoxyphenyl)propen-2-oyl chloride 
• 81616-80-0 (S)-2(2-methoxyphenyl)propionic acid 

Relevant articles and documents

Rh-Catalyzed Coupling of Acrylic/Benzoic Acids with α-Diazocarbonyl Compounds: An Alternative Route for α-Pyrones and Isocoumarins

A coupling of acrylic acids/benzoic acids with α-diazocarbonyl compounds has been realized by a combined catalytic system of rhodium catalyst and Zn(OAc)2 additive. The presence of Zn(OAc)2 obviously accelerates the C(sp2)

MAXI-K POTASSIUM CHANNEL OPENERS FOR THE TREATMENT OF FRAGILE X ASSOCIATED DISORDERS

The present invention relates to the compounds of formula (I) and pharmaceutical compositions containing these compounds. The compounds provided herein can act as maxi-K potassium channel openers, which makes them suitable for use in therapy, particularly in the treatment or prevention of fragile X associated disorders, such as fragile X syndrome.

Macrolide Synthesis through Intramolecular Oxidative Cross-Coupling of Alkenes

A RhIII-catalyzed intramolecular oxidative cross-coupling between double bonds for the synthesis of macrolides is described. Under the optimized reaction conditions, macrocycles containing a diene moiety can be formed in reasonable yields and with excellent chemo- and stereoselectivity. This method provides an efficient approach to synthesize macrocyclic compounds containing a 1,3-conjugated diene structure.