81633-77-4 Usage
Uses
SKF 38393 Hydrobromide is a derivative of a unique dopamine receptor agonist.
Biological Activity
Prototypical D 1 -like dopamine receptor selective partial agonist (K i values are 1, ~ 0.5, ~ 150, ~ 5000 and ~ 1000 nM for D 1 , D 5 , D 2 , D 3 and D 4 receptors respectively).
Check Digit Verification of cas no
The CAS Registry Mumber 81633-77-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,6,3 and 3 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 81633-77:
(7*8)+(6*1)+(5*6)+(4*3)+(3*3)+(2*7)+(1*7)=134
134 % 10 = 4
So 81633-77-4 is a valid CAS Registry Number.
InChI:InChI=1/C16H17NO2.BrH/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11;/h1-5,8-9,14,17-19H,6-7,10H2;1H
81633-77-4Relevant articles and documents
Absolute stereochemistry and dopaminergic activity of enantiomers of 2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine
Kaiser,Dandridge,Garvey,Hahn,Sarau,Setler,Bass,Clardy
, p. 697 - 703 (2007/10/02)
Resolution of the unique dopamine receptor agonist 2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine (1) was achieved by a stereospecific multistep conversion of the readily separated enantiomers of its O,O,N-trimethylated diffractometric analysi
