816457-61-1

Basic information

• Product Name: Benzenepropanoic acid, a-methylene-b-[[[2-(trimethylsilyl)ethyl]sulfonyl]amino]-, methyl ester
• CAS NO: 816457-61-1
• Molecular Formula: C16H25NO4SSi
• Molecular Weight: 355.53
• Mol File: 816457-61-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenepropanoic acid, a-methylene-b-[[[2-(trimethylsilyl)ethyl]sulfonyl]amino]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoic acid, a-methylene-b-[[[2-(trimethylsilyl)ethyl]sulfonyl]amino]-, methyl ester(816457-61-1)
• EPA Substance Registry System: Benzenepropanoic acid, a-methylene-b-[[[2-(trimethylsilyl)ethyl]sulfonyl]amino]-, methyl ester(816457-61-1)

Safety Data

• Hazardous Substances Data: 816457-61-1(Hazardous Substances Data)

Upstream product

• 125486-96-6 2-(trimethylsilyl)ethanesulfonamide 
• 100-52-7 benzaldehyde 
• 292638-85-8 acrylic acid methyl ester 

Downstream Products

• 915777-71-8 8-methoxy-3-phenyl-2-(2-(trimethylsilanyl)ethylsulfonyl)-2,3-dihydro-1H-benzo[c]azepine-4-carboxylic acid methyl ester 
• 915777-72-9 8-fluoro-3-phenyl-2-(2-(trimethylsilanyl)ethylsulfonyl)-2,3-dihydro-1H-benzo[c]azepine-4-carboxylic acid methyl ester 
• 915777-70-7 3-phenyl-2-(2-(trimethylsilanyl)ethylsulfonyl)-2,3-dihydro-1H-benzo[c]azepine-4-carboxylic acid methyl ester 
• 212071-06-2 methyl 2-phenyl-1-(2-(trimethylsilyl)ethylsulfonyl)-2,5-dihydro-1H-pyrrole-3-carboxylate 
• 52179-69-8 methyl 2-phenyl-1H-pyrrole-3-carboxylate 
• 915777-58-1 methyl 2-((N-2-bromobenzyl-2-(trimethylsilyl)ethan-3-ylsulfonamido)(phenyl)methyl)acrylate 
• 915777-60-5 methyl 2-((N-2-bromo-5-fluoro-benzyl-2-(trimethylsilyl)ethan-3-ylsulfonamido)(phenyl)methyl)acrylate 
• 915777-59-2 methyl 2-((N-2-bromo-5-methoxy-benzyl-2-(trimethylsilyl)ethan-3-ylsulfonamido)(phenyl)methyl)acrylate 
• 816457-76-8 methyl 2-((N-allyl-2-(trimethylsilyl)ethan-3-ylsulfonamido)(phenyl)methyl)acrylate 

Relevant articles and documents

2-Trimethylsilylethanesulfonyl (SES) versus tosyl (Ts) protecting group in the preparation of nitrogen-containing five-membered rings. A novel route for the synthesis of substituted pyrrolines and pyrrolidines

(Chemical Equation Presented) The 2-trimethylsilylethanesulfonyl (or SES) protecting group was compared to the tosyl (Ts) group in the preparation of a nitrogen-containing five-membered ring obtained by the aza-Baylis - Hillman/alkylation/RCM route. While

Sequential aza-Baylis-Hillman/ring closing metathesis/aromatization as a novel route for the synthesis of substituted pyrroles

A new route to diverse 2-substituted-3-methoxycarbonyl pyrroles has been developed. Diverse SES protected α-methylene β-aminoesters were obtained by a 3-component aza-Baylis-Hillman reaction. Diversity arose from the aryl aldehydes which can be used in th