81683-54-7

Basic information

• Product Name: C₁₂H₈Cl₂N₂O₂
• Synonyms: C₁₂H₈Cl₂N₂O₂
• CAS NO: 81683-54-7
• Molecular Weight: 283.114
• Mol File: 81683-54-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₂H₈Cl₂N₂O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂H₈Cl₂N₂O₂(81683-54-7)
• EPA Substance Registry System: C₁₂H₈Cl₂N₂O₂(81683-54-7)

Safety Data

• Hazardous Substances Data: 81683-54-7(Hazardous Substances Data)

Upstream product

• 106-47-8 4-chloro-aniline 
• 81683-51-4 α-chloro-1-(2-furyl)-1,3-butanedione 

Downstream Products

• 1187529-18-5 6-(4-chlorophenyl)-8-(2-furoyl)-9-phenyl-1,4,6,7,9-thiatetrazaspiro[4.4]non-7-en-3-one 
• 1028158-72-6 4-benzoylamino-1-(4-chlorophenyl)-5-ethyl-3-(2-furoyl)-4,5-dihydro-1H-1,2,4-triazole 
• 1028158-70-4 4-acetylamino-1-(4-chlorophenyl)-3-(2-furoyl)-5-methyl-4,5-dihydro-1H-1,2,4-triazole 
• 1028158-74-8 1-(4-chlorophenyl)-5-cyclohexyl-3-(2-furoyl)-4-methoxycarbonylamino-4,5-dihydro-1H-1,2,4-triazole 
• 81683-80-9 N-[3-(4-Chloro-phenyl)-5-(furan-2-carbonyl)-3H-[1,3,4]thiadiazol-(2E)-ylidene]-benzamide 
• 81683-76-3 N-[3-(4-Chloro-phenyl)-5-(furan-2-carbonyl)-3H-[1,3,4]thiadiazol-(2E)-ylidene]-acetamide 
• 81683-69-4 C₁₃H₇ClN₄O₃S 
• 81683-62-7 2-(4-Chloro-phenyl)-7-furan-2-yl-3,4-dimethyl-2H-pyrazolo[3,4-d]pyridazine 
• 81683-72-9 3-(4-Chloro-phenyl)-5-(furan-2-carbonyl)-3H-[1,3,4]thiadiazol-2-one 
• 81690-93-9 [4-(4-Chloro-phenyl)-5-imino-4,5-dihydro-[1,3,4]thiadiazol-2-yl]-furan-2-yl-methanone 
• 81683-58-1 1-[1-(4-Chloro-phenyl)-3-(furan-2-carbonyl)-5-methyl-1H-pyrazol-4-yl]-ethanone 

Relevant articles and documents

S1P3 RECEPTOR ANTAGONIST

The present invention relates to a medicine, and more particularly to novel arylamidrazone derivatives having an antagonistic action against S1P3 receptors and a medicine containing thereof as an active ingredient. The present invention provides an arylamidrazone derivative represented by' the following formula (1) or a pharmaceutically acceptable salt thereof: wherein R1 represents a C2-C8 alkyl group which maybe substituted, a phenyl group which maybe substituted, an aromatic heterocyclic group which may be substituted, a C2-C8 alkoxy group which may be substituted, or -NR4R5 (wherein R4 and R5, which are identical or different, each represent a hydrogen atom or a lower alkyl group which may be substituted, or R4 and R5 may be joined with the adjacent nitrogen atom to form a nitrogen-containing heterocyclic ring which may be substituted); R2 and R3, which are identical or different, each represent a hydrogen atom, a halogen atom, a halo-lower alkyl group, a lower alkyl group, a lower alkynyl group, a lower alkoxy group, a cyano group, a lower alkanoyl group or a lower alkylsulfonyl group; A represents a benzene ring or a heterocyclic ring; D represents a single bond or methylene; m represents an integer from 1 to 3, and n represents an integer from 1 to 5 (with the proviso that the case where R1 is an ethoxy group, R2 is a 2,4-dichloro group, R3 is a hydrogen atom, A is a benzene ring, and D is methylene; and the case where R1 is an ethoxy group, R2 is a 2,4-dichloro group, R3 is a hydrogen atom, a 2-methyl group, a 4-methyl group, a 4-methoxy group or a 4-ethoxy group, A is a benzene ring, and D is a single bond, are excluded).