81795-19-9Relevant articles and documents
Inhibition of NADH oxidation by 1-methyl-4-phenylpyridinium analogs as the basis for the prediction of the inhibitory potency of novel compounds
Sablin, Sergey O.,Krueger, Matthew J.,Yankovskaya, Victoria L.,Tkachenko, Sergey E.,Razdolsky, Alexander N.,Bachurin, Sergey O.,Ramsay, Rona R.,Singer, Thomas P.
, p. 33 - 43 (2007/10/03)
Inhibition of NADH dehydrogenase (Complex I) of the mitochondrial respiratory chain by 1-methyl-4-phenylpyridinium (MPP+) and its analogs results in dopaminergic cell death. In the present study, the inhibition of mitochondrial respiration and
